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OPSC Scientific Officer Toxicology Syllabus 2027, Exam Pattern
OPSC Scientific Officer Toxicology Syllabus 2027, Exam Pattern, Exam Date 2027
Detail Information about OPSC has published notification 2027 for the recruitment of Scientific Officer (Toxicology) vacancies. Those Candidates who are Interested to the following vacancy and completed all Eligibility Criteria can read the Notification & Apply Online. In this page we provide the Complete Syllabus of this Recruitment with Latest Update Exam Pattern and the Exam Date also.
OPSC Scientific Officer (Toxicology) Syllabus 2027 - Overview
| Exam Conducting Authority | Odisha Public Service Commission (OPSC) |
| Name of the Post | Scientific Officer (Toxicology) |
| Total Vacancies | 13 |
| Exam Date 2027 | 17th January 2027 |
| Job Location | Odisha |
| Category | Syllabus and Exam Pattern |
| Official Website | www.opsc.gov.in |
OPSC Scientific Officer (Toxicology) Syllabus 2027
Paper - I
General English
1. Synonyms
2. Antonyms
3. Use of common phrases & Idioms
4. Use of appropriate Prepositions and Comprehension
5. Ordering of words in a sentence
6. Ordering of sentences
7. Spotting of errors
8. Use of appropriate and qualifying words
General Awareness, General Aptitude and Reasoning
1. Reasoning
2. Aptitude
3. Data interpretation and general awareness on Science
4. Current affairs
5. Geography
6. History of India and Odisha
7. Indian constitution
8. Socio Economic Political Developments
9. Human right
10. Fundamentals of Computer
11. Psychology
12. General Awareness
Paper - II
Concerned Subject (Toxicology)
Unit I
Analytical Chemistry: Classification of analytical methods - Classical and Instrumental, volumetric, titrimetric and gravimetric techniques, selection of proper analytical techniques: types and range of determination, accuracy, precision and errors, sample preparation, handling of reagents with safety, density and viscosity measurements.
Statistical Analysis : Mean, Mode, Median, Correlation and Regression analysis, Null Hypothesis, Variance, t-test, Chi-Square test. Type of Data, Measure of central tendency, Dispersion of Data, Correlation, Probability and Proof.
Group Theory: Symmetry elements and operations; Point groups and character tables; Internal coordinates and vibrational modes; symnetry adapted linear combination of atomic orbitals
(LCAO-MO); construction of hybrid orbitals using symmetry aspects.
Electrochemistry: Electrochemical cells and cell reactions; Standard electrode potentials; Nernst equation and its relation to AG; Electrochemical series, emf of galvanic cells; Faraday's laws of electrolysis; Electrolytic conductance, specific, equivalent and molar conductivity, Kohlrausch's law; Concentration cells.
Unit II
Analysis of unknown samples -
Organic: Physical examination, element detection (N, S, Cl, Br, I, F), Functional Group analysis (-ОН, -СОOH, -NO2, -NH2, -CONH2, -CO-, -CHO, Hydrocarbons).
Reaction Mechanisms: Basic mechanistic concepts - kinetic versus thermodynamic control, Hammond's postulate and Curtin-Hammett principle. Methods of determining reaction mechanisms through kinetics, identification of products, intermediates and isotopic labelling.Linear free-energy relationship - Hammett and Taft equations.Nucleophilic and electrophilic substitution reactions (both aromatic and aliphatic).Addition reactions to carboncarbon and carbon-heteroatom (N and O) multiple bonds.Elimination reactions. Reactive
intermediates - carbocations, carbanions, carbenes, nitrenes, arynes and free radicals. Molecular rearrangements.
Pericyclic Reactions and Photochemistry: Electrocyclic, cycloaddition and sigmatropic reactions. Orbital correlations FMO and PMO treatments, Woodward-Hoffmann rule. Photochemistry of alkenes, arenes and carbonyl compounds. Photooxidation and photoreduction.Di-π-methane rearrangement, Barton-McCombie reaction, Norrish type-I and II cleavage reaction.
Inorganic: Qualitative analysis of cations and anions with special reference to cations i.e. As, Sb, Pb, Ba, Cu, Hg, Zn and Tl and anions i.e.NO₂, NO,S₂, SO4². SO₂2 halides and cyanides.
Main Group Elements: Hydrides, halides, oxides, oxoacids, nitrides, sulfides - shapes and reactivity. Structure and bonding of boranes, carboranes, silicones, silicates, boron nitride, borazines and phosphazenes.Allotropes of carbon, phosphorous and sulphur.Industrial synthesis of compounds of main group elements.Chemistry of noble gases, pseudohalogens, and interhalogen compounds.Acid-base concepts and principles (Lewis, Bronsted, HSAB and acidbase catalysis).
Transition Elements: Coordination Chemistry - structure and isomerism, theories of bonding (VBT, CFT, and MOT). Energy level diagrams in various crystal fields, CFSE, applications of CFT, JahnTeller distortion. Electronic spectra of transition metal complexes: spectroscopic term symbols, selection rules, Orgel and Tanabe-Sugano diagrams, nephelauxetic effect and Racah parameter, charge-transfer spectra. Magnetic properties of transition metal complexes. Ray-Dutt and Bailar twists, Reaction mechanisms: kinetic and thermodynamie stability, substitution and redox reactions. Metal-metal muitiple bond.
Analysis of poisonous gases: CO, H2S, PH3, CH4 and NH3.
Salt Analysis
Unit-III
Spectroscopic and other techniques:-
Unifying principles : Electromagnetic radiation, interaction of electromagnetic radiation with matter- absorption, emission, transmission, reflection, refraction, dispersion, polarization and scattering. Basic principles, instrumentation and applications: UV- Visible, FTIR, AAS, Mass, Spectroscopy, Fluorescence and Phosphorescence spectrophotometry, ESR. Fundamentals of Acids, Bases and Buffers, pH, pKa, and pKb values, principles, instrumentation and applications of pH metry, Potentiometry, Conductometry and Microscopic analysis in forensic science.
Unit-IV
Chromatography and Electrophoresis: General Principles and types of chromatographic techniques: Paper chromatography, column chromatography, Thin layer chromatography, absorption chromatography, partition chromatography, Gas chromatography, Gas-liquid chromatography, Ion exchange chromatography, Exclusion (permeation) chromatography, affinity chromatography, HPLC, HPTLC, HPTLC MS, Capillary Chromatography and Electrophoresis.
Unit-V
Basic Organic Chemistry: Important preparations and properties of alkanes, alkenes, alkynes, aromatic hydrocarbons, alcohols, phenols, carboxylic acids, aldehydes, ketones, amines and nitro compounds.
Unit-VI
Proteins: Classification, Structure and Properties, Molecular weight determination, Isoelectric point, coagulation and denaturation. Carbohydrates: Classification, Structure and Reactions. Fats and Lipids: Classification, Structure and Reactions. Alkaloids: Classification, Isolation and Identification.
Unit-VII
Forensic Toxicological examination and significance, Poison: Definition, classification, mode of action, chemical nature, methods of poison administration, Classification of poisoning : Accidental, homicidal and suicidal. Symptoms of poisoning and antidotes, Collection and preservation of toxicological exhibits in poisoning cases. Postmortem examination and postmortem changes, Medicolegal aspects of wounds, Modes of death.
Unit-VIII
Different methods of extraction and isolation of poisons from visceral organs and other biological specimens: Solvent extraction, distillation/steam distillation, micro diffusion, dialysis, dry ashing and wet digestion.
Pharmacology: Metabolism and excretion of poisons - Introduction, pathways of drug metabolism, nonsynthetic and synthetic pathways like oxidation, hydroxylation,. N-and Оdealkylation, sulphoxide formation, conjugation, acetylation, methylation of drugs/poisons as exemplified by alcohols, aldehydes, ketones, aliphatic amines, phenols, cyanide, barbiturates, opiates, benzodiazepines and amphetamines.
Unit-IX
Analysis of volatile poisons, toxic metals and non-metallic anions in biological fluids. Analysis of pesticides :Organochlorinated, Organophosphorous, Synthetic pyrethroids, Carbamates, Aluminium phosphide and Zinc phosphide in visceral tissues.
Unit-X
Methods of analysis of acidic and neutral drugs in biological fluids, salicylic acid, benzoic acid, aspirin, meprobamate, barbiturates etc. Method of analysis of basic drugs of abuse from biological specimens: Opium and its alkaloids, atropine, strychnine, brucine, cocaine, amphetamines and its derivatives, benzodiazepines, LSD, ketamine, methaqualone and nicotine.
Method of analysis of mechanical poisons- Glass, diamond and hair. Plant poisons and their examination :Dhatura, Atropa belladonna, Marking nut, Nux vomica, Oleander, Aconite, Abrus, Cannabis, Croton and poisonous fungi
OPSC Scientific Officer (Toxicology) Exam Pattern 2027
Negative Marking : 0.25 (Each Paper)
| Paper | Subject | No. of Question | Marks | Duration |
| Paper I | General English | 50 | 50 | 1 Hour & 30 Minutes |
| General Awareness, General Aptitude and Reasoning | 50 | 50 | ||
| Paper II | Concerned Subject (Toxicology) | 150 | 300 | 2 Hour & 30 Minutes |
| Total | 250 | 400 | 4 Hours |
Exam Date 2027 : 17th January 2027
Starting Date of Application Form : 06th November 2026
Last Date of Application Form : 26th November 2026
Total Post : 13
Last Date of Application Form : 26th November 2026
Total Post : 13
FAQs
OPSC Scientific Officer Toxicology 2027 Exam Syllabus Frequently Asked Questions (FAQ's)
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