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GPAT 2023 Syllabus
Physical Chemistry
1. Composition and Physical States of Matter
2. Colligative properties
3. Thermodynamics
4. Refractive Index
5. Solutions
6. Electrochemistry
7. Ionic Equilibrium
8. Kinetics
Physical Pharmacy
1. Matter
2. Properties of Matter
3. Micromeritics and powder rheology
4. Surface and interfacial phenomenon
5. Viscosity and rheology
6. Dispersion systems
7. Complexation
7. Buffer
8. Solubility
Organic Chemistry
1. General Principles
2. Different classes of compounds
3. Protection & deprotection of groups
4. Aromaticity & chemistry of aromatic compounds
5. Different aromatic classes of compounds
6. Polycyclic aromatic hydrocarbons
7. Carbonyl Chemistry
8. Heterocyclic Chemistry
9. Bridged rings
10. Kinetic & thermodynamic control
11. Stereochemistry
12. Carbohydrates
13. Amino Acids and Proteins
14. Pericyclic reactions
Pharmaceutical Chemistry
Pharmaceutical Chemistry is divided into two parts, i.e. Pharmaceutical Inorganic Chemistry and Medicinal Chemistry. Below are the topics that should be covered for the same.
Pharmaceutical Inorganic Chemistry– Pharmaceutical Impurities, Monographs, Isotopes, Dentifrices, desensitizing agents, & anticaries agents.
Medicinal Chemistry- Therapeutic classes of drugs, Various classes of therapeutic agents, Different classes of therapeutic drugs.
Pharmaceutics
1. Pharmacy Profession & Introduction to Pharmaceuticals
2. Introduction to dosage form
3. Sources of drug information
4. Allopathic dosage form
5. Crude extract
6. Allergenic extract
7. Biological products
8. Pharmaceutical Plant location, layout
9. Dosage Form Necessities and Additives
10. Powders
11. Capsules
12. Tablets
13. Parenterals – product requiring sterile packaging
14. Suspensions
15. Emulsions
16. Suppositories
17. Semisolids
18. Liquids (solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses)
19. Pharmaceutical Aerosols
20. Ophthalmic preparations
21. Preformulations
22. Stability of formulated products
23. Prolonged Action Pharmaceuticals
24. Novel Drug delivery system
25. GMP and Validation
26. Packaging Materials, Cosmetics
27. Pilot plant scale-up techniques
Pharmacology
1. General Pharmacology
2. Neurohumoral transmission in the autonomic and central nervous system
3. Pharmacology of peripheral nervous system
4. Pharmacology of central nervous System
5. Pharmacology of cardiovascular system
6. Drugs acting on the urinary system
7. Drugs acting on Respiratory system
8. Pharmacology of Endocrine system
9. Chemotherapy
10. Autacoids and their Antagonists
11. Pharmacology of drug acting on the gastrointestinal tract
12. Chronopharmacology
13. Immunopharmacology
14. Vitamins & Minerals
15. Principles of toxicology
Pharmacognosy
1. Introductory Pharmacognosy
2. Classification of crude drugs
3. Factors influencing the quality of crude drugs,
4. Techniques in microscopy
5. Introduction to phytoconstituents
6. Principles of plant classification
7. Pharmaceutical aids
8. Animal products
9. Plant products
10. Toxic drugs
11. Enzymes
12. Homeopathic system of medicine
13. Ayurvedic system of medicine
14. Patents
15. Plants based industries and research institutes in India
16. Herbal cosmetics
17. Worldwide trade of crude drugs and volatile oils
18. Phytopharmaceuticals
Pharmaceutical Analysis
1. Importance of quality control in pharmacy
2. Oxidation-reduction titrations
3. Non-aqueous titrations
4. Precipitation titrations
5. Complexometric titrations
6. Gravimetry
7. Extraction techniques
8. Potentiometry
9. Calibration
10. General principles of spectroscopy
11. Spectrofluorimetry
12. Ultraviolet-visible Spectrometry
13. Flame photometry & atomic absorption spectrometry
14. Mass spectrometry
15. Polarography
16. Nephelometry & Turbidimetry
17. Chromatography
Biochemistry
1. Cells
2. Carbohydrates
3. Proteins
4. Lipids
5. Vitamins
6. Biological oxidations & reductions
7. Enzymes
8. Nucleic acids
9. Hereditary diseases.
Biotechnology
1. Plant Cell and Tissue Culture
2. Animal Cell Culture
3. Fermentation Technology and Industrial Microbiology
4. Recombinant DNA Technology, Biotechnology Derived Products
Microbiology
1. Introduction to Microbiology
2. Microscopy and staining technique
3. Biology of Microorganisms
4. Fungi and Viruses
5. Sterilization & Disinfection
6. Microbial Assay
7. Vaccines & Sera
Pathophysiology
1. Basic principles of cell injury and adaptation
2. Basic mechanisms of inflammation and repair
3. Disorders of fluid
4. Electrolyte and acid-base balance
5. Immunopathology including amyloidosis
6. Infectious diseases
7. Hepatitis – Infective hepatitis
8. Neoplastic diseases
9. Pathophysiology of common diseases
10. Laboratory tests for Liver function tests and kidney function tests
Biopharmaceutics and Pharmacokinetics
1. Bio-pharmaceutics
2. Bioavailability & Bioequivalence
3. Quality parameters of dosage forms
4. Assay methods & its validation
5. Biopharmaceutical statistics
Clinical Pharmacy and Therapeutics
1. General Principles, preparation, maintenance, analysis of observational records in clinical Pharmacy.
2. Clinical trials, type and phases of clinical trials, placebo, ethical and regulatory issues including Good clinical practice in clinical trials.
3. Therapeutic drug monitoring, adverse drug reaction (ADR), types of ADR, Mechanism of ADR. Drug interaction, Monitoring and reporting of ADR and its significance.
4. Drug information services, Drug interactions.
5. Drug interaction in pediatric and geriatric patients, drug treatment during pregnancy,
6. lactation and menstruation.
7. Pharmacovigilance, Therapeutic drug monitoring, Nutraceuticals, essential drugs and
8. rational drug usage.
9. Age-related drug therapy: concept of posology, drug therapy for neonates, pediatrics and
11. geriatrics. Drugs used in pregnancy and lactation.
11. Drug therapy in gastrointestinal, hepatic, renal, cardiovascular and respiratory Disorders.
12. Drug therapy for neurological and psychological disorders.
13. Drug therapy in infections of respiratory system, urinary system, infective meningitis, TB,
14. HIV, malaria and filaria.
15. Drug therapy for thyroid and parathyroid disorders, diabetes mellitus, menstrual cycle
16. disorders, menopause and male sexual dysfunction.
17. Drug therapy for malignant disorders like leukemia, lymphoma and solid tumors.
18. Drug therapy for rheumatic, eye and skin disorders.
Human Anatomy and Physiology
1. Cell physiology
2. The Blood
3. Gastrointestinal tract,
4. Respiratory System
5. Autonomic nervous system
6. Sense organs
7. Skeletal System
8. Central Nervous system
9. Urinary System,
10. Endocrine Glands
11. Reproductive System
12. Cardiovascular system
13. Lymphatic system
Pharmaceutical Engineering
1. Fluid flow,
2. Heat transfer
3. Evaporation
4. Distillation
5. Drying
6. Size reduction and size separation
7. Extraction
8. Mixing
9. Crystallization
10. Filtration and Centrifugation
11. Dehumidification and humidity control
12. Refrigeration and air conditioning
13. Material of constructions
14. Automated process control systems
15. Industrial hazards & safety precautions
Pharmaceutical Management
1. Introduction to management
2. Planning and Forecasting
3. Organization
4. Research Management
5. Inventory Management
6. Communication,
7. Marketing Research
8. Leadership and motivation
9. Human resource and development (HRD),
10. GATT
11. World trade organization (WTO) and trade-related intellectual property rights (TRIPS)
12. Standard institutions and regulatory authorities
13. Bureau of Indian Standards (BIS)
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