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Objective Questions

Latest BFUHS Pharmacist Exam Question (Objective Questions), MCQ in English

Subjects : Concerned Subject (Pharmacist)

Question Bank BFUHS Pharmacist Exam - English
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Concerned Subject (Pharmacist)

Question 1Single Answer
Which is an important advantage of liposomes as drug-delivery carriers?
  1. A
    Ability to encapsulate both hydrophilic and lipophilic drugs
  2. B
    Guaranteed elimination of drug toxicity
  3. C
    Mandatory rapid renal clearance
  4. D
    Complete prevention of drug degradation in every formulation
Question 2Single Answer
Liposomes are primarily composed of:
  1. A
    Polysaccharides
  2. B
    Proteins
  3. C
    Phospholipids
  4. D
    Nucleic acids
Question 3Single Answer
The aqueous cavity of a liposome is best suited for encapsulating:
  1. A
    Hydrophobic drugs
  2. B
    Lipophilic drugs
  3. C
    Hydrophilic drugs
  4. D
    Gaseous drugs
Question 4Single Answer
Which method is commonly used for the preparation of multilamellar vesicles (MLVs)?
  1. A
    Sonication
  2. B
    Extrusion
  3. C
    Thin-film hydration
  4. D
    Reverse-phase evaporation
Question 5Single Answer
Sterically stabilized liposomes, often referred to as "stealth liposomes," are modified with which polymer to prolong circulation time?
  1. A
    Polyvinylpyrrolidone (PVP)
  2. B
    Polyethylene glycol (PEG)
  3. C
    Hydroxypropyl methylcellulose (HPMC)
  4. D
    Ethylcellulose
Question 6Single Answer
Under the commonly used general definition, nanoparticles have dimensions approximately within which range?
  1. A
    1–100 nm
  2. B
    1–1000 µm
  3. C
    1–10 mm
  4. D
    10–100 cm
Question 7Single Answer
Which of the following materials is commonly used for the fabrication of polymeric nanoparticles?
  1. A
    Gold
  2. B
    Silicon dioxide
  3. C
    Polylactic acid (PLA)
  4. D
    Carbon nanotubes
Question 8Single Answer
Nanoparticles can enhance drug delivery by:
  1. A
    Increasing first-pass metabolism
  2. B
    Promoting drug degradation
  3. C
    Improving drug penetration across biological barriers
  4. D
    Enhancing non-specific drug distribution
Question 9Single Answer
Which of the following is a method for preparing nanoparticles by precipitation?
  1. A
    Emulsification-solvent evaporation
  2. B
    Nanoprecipitation
  3. C
    High-pressure homogenization
  4. D
    Spray drying
Question 10Single Answer
The enhanced permeability and retention effect has traditionally been associated with passive accumulation of nanocarriers particularly in?
  1. A
    Some solid tumors with abnormal vasculature
  2. B
    All healthy tissues equally
  3. C
    Normal intact brain tissue universally
  4. D
    Every organ regardless of vascular properties
Question 11Single Answer
Which of the following is a solid unit dosage form intended for oral use?
  1. A
    Syrup
  2. B
    Elixir
  3. C
    Tablet
  4. D
    Tincture
Question 12Single Answer
Hard gelatin capsules are primarily composed of?
  1. A
    Gelatin
  2. B
    Cellulose
  3. C
    Pectin
  4. D
    Dextrin
Question 13Single Answer
Which dosage form is best suited for pediatric patients?
  1. A
    Tablet
  2. B
    Capsule
  3. C
    Suppository
  4. D
    Syrup
Question 14Single Answer
Enteric-coated tablets are designed to?
  1. A
    Mask bitter taste
  2. B
    Dissolve in the stomach
  3. C
    Increase disintegration rate
  4. D
    Protect from gastric acid
Question 15Single Answer
A semisolid dosage form for external application is?
  1. A
    Ointment
  2. B
    Syrup
  3. C
    Lotion
  4. D
    Elixir
Question 16Single Answer
Parenteral preparations must always be?
  1. A
    Sweetened
  2. B
    Sterile
  3. C
    Colored
  4. D
    Chewable
Question 17Single Answer
Which dosage form contains a high concentration of sugar?
  1. A
    Elixir
  2. B
    Tincture
  3. C
    Syrup
  4. D
    Injection
Question 18Single Answer
Which is a liquid oral dosage form prepared by dissolving drugs in alcohol?
  1. A
    Emulsion
  2. B
    Lotion
  3. C
    Tincture
  4. D
    Suspension
Question 19Single Answer
Soft gelatin capsules commonly contain?
  1. A
    Aqueous solutions
  2. B
    Powders only
  3. C
    Oils
  4. D
    Effervescent granules
Question 20Single Answer
Sustained-release tablets are used to?
  1. A
    Increase dosing frequency
  2. B
    Reduce drug absorption
  3. C
    Maintain drug levels longer
  4. D
    Cause rapid onset
Question 21Single Answer
Pharmacokinetics primarily deals with?
  1. A
    Drug effects on body
  2. B
    Body effects on drug
  3. C
    Drug manufacturing process
  4. D
    Drug storage conditions
Question 22Single Answer
Absorption of drugs is defined as?
  1. A
    Excretion of drug
  2. B
    Distribution of drug in tissues
  3. C
    Metabolism of drug
  4. D
    Movement of drug into bloodstream
Question 23Single Answer
Bioavailability of a drug refers to?
  1. A
    Rate of metabolism
  2. B
    Drug toxicity level
  3. C
    Fraction of drug reaching systemic circulation
  4. D
    Drug binding to receptors
Question 24Single Answer
First-pass metabolism occurs in?
  1. A
    Kidney
  2. B
    Lungs
  3. C
    Liver
  4. D
    Skin
Question 25Single Answer
Volume of distribution indicates?
  1. A
    Drug potency
  2. B
    Drug concentration in plasma
  3. C
    Extent of drug distribution in body
  4. D
    Drug clearance rate
Question 26Single Answer
Half-life of a drug is?
  1. A
    Time for plasma concentration to reduce by half
  2. B
    Time to eliminate all drug
  3. C
    Time to reach peak effect
  4. D
    Time for absorption
Question 27Single Answer
Steady state concentration is achieved after?
  1. A
    1 half-life
  2. B
    2 half-lives
  3. C
    4–5 half-lives
  4. D
    10 half-lives
Question 28Single Answer
Drug receptor interaction is best explained by?
  1. A
    Chemical kinetics
  2. B
    Diffusion theory
  3. C
    Osmosis theory
  4. D
    Lock and key theory
Question 29Single Answer
Agonist is a drug that?
  1. A
    Blocks receptor
  2. B
    Has no receptor affinity
  3. C
    Activates receptor
  4. D
    Decreases enzyme activity
Question 30Single Answer
Antagonist is a drug that?
  1. A
    Activates receptor
  2. B
    Blocks receptor action
  3. C
    Increases metabolism
  4. D
    Enhances absorption
Question 31Single Answer
Competitive antagonism is?
  1. A
    Irreversible binding
  2. B
    Binding at different site
  3. C
    Reversible binding at same site
  4. D
    No receptor binding
Question 32Single Answer
Parasympathetic neurotransmitter is?
  1. A
    Dopamine
  2. B
    Acetylcholine
  3. C
    Serotonin
  4. D
    Histamine
Question 33Single Answer
Sympathetic neurotransmitter is mainly?
  1. A
    Acetylcholine
  2. B
    Glutamate
  3. C
    GABA
  4. D
    Noradrenaline
Question 34Single Answer
Beta blockers act on?
  1. A
    Muscarinic receptors
  2. B
    Beta adrenergic receptors
  3. C
    Dopamine receptors
  4. D
    Histamine receptors
Question 35Single Answer
Atropine is an example of?
  1. A
    Muscarinic antagonist
  2. B
    Adrenergic agonist
  3. C
    Beta blocker
  4. D
    Calcium channel blocker
Question 36Single Answer
CNS depressants include?
  1. A
    Caffeine
  2. B
    Nicotine
  3. C
    Amphetamines
  4. D
    Benzodiazepines
Question 37Single Answer
Morphine acts primarily on?
  1. A
    Dopamine receptors
  2. B
    Adrenergic receptors
  3. C
    Opioid receptors
  4. D
    Histamine receptors
Question 38Single Answer
Antiepileptic drug is?
  1. A
    Diazepam
  2. B
    Paracetamol
  3. C
    Aspirin
  4. D
    Phenytoin
Question 39Single Answer
ACE inhibitors are used in?
  1. A
    Hypertension
  2. B
    Diabetes
  3. C
    Asthma
  4. D
    Epilepsy
Question 40Single Answer
Digoxin is used in?
  1. A
    Heart failure
  2. B
    Asthma
  3. C
    Diabetes
  4. D
    Infection
Question 41Single Answer
Diuretics increase?
  1. A
    Blood viscosity
  2. B
    Oxygen demand
  3. C
    Heart rate
  4. D
    Urine output
Question 42Single Answer
Salbutamol is used in?
  1. A
    Hypertension
  2. B
    Epilepsy
  3. C
    Diabetes
  4. D
    Asthma
Question 43Single Answer
Insulin is secreted by?
  1. A
    Alpha cells
  2. B
    Delta cells
  3. C
    Beta cells
  4. D
    Liver
Question 44Single Answer
Thyroid hormone regulates?
  1. A
    Blood pressure
  2. B
    Metabolism
  3. C
    Digestion only
  4. D
    Immunity only
Question 45Single Answer
Antibiotics act on?
  1. A
    Viruses only
  2. B
    Parasites only
  3. C
    Fungi only
  4. D
    Bacteria
Question 46Single Answer
Penicillin works by inhibiting?
  1. A
    Protein synthesis
  2. B
    Cell wall synthesis
  3. C
    DNA replication
  4. D
    RNA synthesis
Question 47Single Answer
Tetracycline inhibits?
  1. A
    50S ribosome
  2. B
    30S ribosome
  3. C
    DNA gyrase
  4. D
    Cell wall
Question 48Single Answer
Antifungal drug is?
  1. A
    Fluconazole
  2. B
    Amoxicillin
  3. C
    Rifampicin
  4. D
    Streptomycin
Question 49Single Answer
Antiviral drug is?
  1. A
    Tetracycline
  2. B
    Penicillin
  3. C
    Cephalosporin
  4. D
    Acyclovir
Question 50Single Answer
Cancer chemotherapy targets?
  1. A
    Only viruses
  2. B
    Only fungi
  3. C
    Only bacteria
  4. D
    Rapidly dividing cells
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