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Latest BTSC SMO Orthopedics Exam Question (Objective Questions), MCQ in English

Subjects : Orthopedics

Question Bank BTSC Specialist Medical Officer (Orthopedics) Exam - English
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Orthopedics

Question 1Single Answer
Primary hyperparathyroidism is most commonly caused by:
  1. A
    Vitamin D deficiency
  2. B
    Parathyroid adenoma
  3. C
    Chronic kidney disease
  4. D
    Malabsorption syndromes
Question 2Single Answer
A hallmark laboratory finding in primary hyperparathyroidism is:
  1. A
    Hypocalcemia
  2. B
    Hypercalcemia
  3. C
    Hypophosphatemia
  4. D
    Hyperphosphatemia
Question 3Single Answer
"Bones, stones, abdominal groans, and psychic moans" is a mnemonic for:
  1. A
    Osteoporosis
  2. B
    Hyperparathyroidism
  3. C
    Renal osteodystrophy
  4. D
    Osteogenesis imperfecta
Question 4Single Answer
Secondary hyperparathyroidism is most commonly caused by:
  1. A
    Parathyroid adenoma
  2. B
    Chronic kidney disease
  3. C
    Vitamin D toxicity
  4. D
    Malignancy
Question 5Single Answer
In secondary hyperparathyroidism, which of the following is typically elevated?
  1. A
    Serum calcium
  2. B
    Serum phosphate
  3. C
    Parathyroid hormone (PTH)
  4. D
    25-hydroxyvitamin D
Question 6Single Answer
"Rugger jersey spine" on X-ray is associated with:
  1. A
    Osteomalacia
  2. B
    Hyperparathyroidism
  3. C
    Renal osteodystrophy
  4. D
    Osteogenesis imperfecta
Question 7Single Answer
The definitive treatment for symptomatic primary hyperparathyroidism is:
  1. A
    Vitamin D supplementation
  2. B
    Bisphosphonates
  3. C
    Parathyroidectomy
  4. D
    Calcium supplementation
Question 8Single Answer
Cinacalcet is used in the medical management of:
  1. A
    Primary hyperparathyroidism
  2. B
    Secondary hyperparathyroidism
  3. C
    Osteoporosis
  4. D
    Osteomalacia
Question 9Single Answer
Sestamibi scan is used to:
  1. A
    Measure bone mineral density
  2. B
    Localize parathyroid adenomas
  3. C
    Assess renal function
  4. D
    Detect fractures
Question 10Single Answer
Subperiosteal bone resorption is a radiographic finding in:
  1. A
    Osteoporosis
  2. B
    Hyperparathyroidism
  3. C
    Osteomalacia
  4. D
    Osteogenesis imperfecta
Question 11Single Answer
Renal osteodystrophy is a complication of:
  1. A
    Diabetes mellitus
  2. B
    Chronic kidney disease
  3. C
    Hyperthyroidism
  4. D
    Hypothyroidism
Question 12Single Answer
Which of the following contributes to the pathophysiology of renal osteodystrophy?
  1. A
    Increased vitamin D activation
  2. B
    Decreased phosphate excretion
  3. C
    Decreased PTH secretion
  4. D
    Increased calcium absorption
Question 13Single Answer
Adynamic bone disease is a type of:
  1. A
    Osteoporosis
  2. B
    Renal osteodystrophy
  3. C
    Osteomalacia
  4. D
    Osteogenesis imperfecta
Question 14Single Answer
Which medication is used to control hyperphosphatemia in renal osteodystrophy?
  1. A
    Vitamin D
  2. B
    Calcium carbonate
  3. C
    Bisphosphonates
  4. D
    Cinacalcet
Question 15Single Answer
Dietary management of renal osteodystrophy includes:
  1. A
    High protein intake
  2. B
    Low phosphate intake
  3. C
    High calcium intake
  4. D
    High vitamin D intake
Question 16Single Answer
Which of the following is used to assess bone turnover in renal osteodystrophy?
  1. A
    Bone mineral density
  2. B
    Bone biopsy
  3. C
    X-ray
  4. D
    Ultrasound
Question 17Single Answer
Calciphylaxis is a severe complication of:
  1. A
    Osteoporosis
  2. B
    Renal osteodystrophy
  3. C
    Osteomalacia
  4. D
    Osteogenesis imperfecta
Question 18Single Answer
Which vitamin D analog is commonly used in renal osteodystrophy?
  1. A
    Vitamin D2
  2. B
    Vitamin D3
  3. C
    Calcitriol
  4. D
    Ergocalciferol
Question 19Single Answer
The goal of treatment in renal osteodystrophy is to maintain:
  1. A
    High serum phosphate
  2. B
    Low serum calcium
  3. C
    Normal PTH levels
  4. D
    Low serum vitamin D
Question 20Single Answer
Which of the following is a clinical feature of renal osteodystrophy?
  1. A
    Increased bone density
  2. B
    Bone pain and fractures
  3. C
    Hypercalcemia
  4. D
    Decreased PTH levels
Question 21Single Answer
Osteogenesis imperfecta is characterized by:
  1. A
    Increased bone density
  2. B
    Brittle bones and fractures
  3. C
    Soft bones and deformities
  4. D
    Increased bone turnover
Question 22Single Answer
The genetic defect in osteogenesis imperfecta primarily affects:
  1. A
    Collagen type I
  2. B
    Collagen type II
  3. C
    Collagen type III
  4. D
    Collagen type IV
Question 23Single Answer
"Blue sclera" is a clinical finding in:
  1. A
    Osteoporosis
  2. B
    Osteogenesis imperfecta
  3. C
    Osteomalacia
  4. D
    Fibrous dysplasia
Question 24Single Answer
Bisphosphonates are used in the management of:
  1. A
    Osteogenesis imperfecta
  2. B
    Fibrous dysplasia
  3. C
    Hypophosphatasia
  4. D
    All of the above
Question 25Single Answer
Fibrous dysplasia is characterized by:
  1. A
    Increased bone density
  2. B
    Replacement of normal bone with fibrous tissue
  3. C
    Soft bones and deformities
  4. D
    Increased bone turnover
Question 26Single Answer
"Shepherd's crook" deformity of the femur is associated with:
  1. A
    Osteoporosis
  2. B
    Osteogenesis imperfecta
  3. C
    Fibrous dysplasia
  4. D
    Osteomalacia
Question 27Single Answer
McCune-Albright syndrome is a form of:
  1. A
    Osteoporosis
  2. B
    Osteogenesis imperfecta
  3. C
    Fibrous dysplasia
  4. D
    Hypophosphatasia
Question 28Single Answer
Hypophosphatasia is characterized by:
  1. A
    Increased bone density
  2. B
    Defective bone mineralization
  3. C
    Soft bones and deformities
  4. D
    Increased bone turnover
Question 29Single Answer
The enzyme deficiency in hypophosphatasia is:
  1. A
    Alkaline phosphatase
  2. B
    Acid phosphatase
  3. C
    Glucocerebrosidase
  4. D
    Galactocerebrosidase
Question 30Single Answer
Which of the following is a clinical feature of hypophosphatasia?
  1. A
    Increased bone density
  2. B
    Premature loss of deciduous teeth
  3. C
    Hypercalcemia
  4. D
    Increased PTH levels
Question 31Single Answer
Teriparatide is used in the treatment of:
  1. A
    Osteoporosis
  2. B
    Osteogenesis imperfecta
  3. C
    Fibrous dysplasia
  4. D
    Hypophosphatasia
Question 32Single Answer
Denosumab is a monoclonal antibody that targets:
  1. A
    RANKL
  2. B
    OPG
  3. C
    Sclerostin
  4. D
    DKK1
Question 33Single Answer
Paget's disease of bone is characterized by:
  1. A
    Increased bone density
  2. B
    Disordered bone remodeling
  3. C
    Soft bones and deformities
  4. D
    Decreased bone turnover
Question 34Single Answer
"Cotton wool" appearance on skull X-ray is associated with:
  1. A
    Osteoporosis
  2. B
    Osteogenesis imperfecta
  3. C
    Paget's disease of bone
  4. D
    Fibrous dysplasia
Question 35Single Answer
Bisphosphonates are used in the management of:
  1. A
    Paget's disease of bone
  2. B
    Fibrous dysplasia
  3. C
    Osteogenesis imperfecta
  4. D
    All of the above
Question 36Single Answer
Achondroplasia is a form of:
  1. A
    Osteoporosis
  2. B
    Dwarfism
  3. C
    Osteomalacia
  4. D
    Fibrous dysplasia
Question 37Single Answer
Achondroplasia is caused by a mutation in the:
  1. A
    FGFR3 gene
  2. B
    COL1A1 gene
  3. C
    ALPL gene
  4. D
    PTH gene
Question 38Single Answer
Rickets is a condition caused by deficiency of:
  1. A
    Calcium
  2. B
    Vitamin D
  3. C
    Phosphate
  4. D
    All of the above
Question 39Single Answer
"Widening of the wrists" is a clinical finding in:
  1. A
    Osteoporosis
  2. B
    Rickets
  3. C
    Osteogenesis imperfecta
  4. D
    Fibrous dysplasia
Question 40Single Answer
Osteomalacia in adults is characterized by:
  1. A
    Increased bone density
  2. B
    Defective bone mineralization
  3. C
    Soft bones and deformities
  4. D
    Increased bone turnover
Question 41Single Answer
The most common cause of osteomalacia is:
  1. A
    Hyperparathyroidism
  2. B
    Vitamin D deficiency
  3. C
    Renal osteodystrophy
  4. D
    Osteogenesis imperfecta
Question 42Single Answer
Looser's zones (pseudofractures) are radiographic findings in:
  1. A
    Osteoporosis
  2. B
    Osteomalacia
  3. C
    Osteogenesis imperfecta
  4. D
    Fibrous dysplasia
Question 43Single Answer
Scurvy is a condition caused by deficiency of:
  1. A
    Vitamin D
  2. B
    Vitamin C
  3. C
    Calcium
  4. D
    Phosphate
Question 44Single Answer
Which of the following is a clinical feature of scurvy?
  1. A
    Increased bone density
  2. B
    Bleeding gums and impaired wound healing
  3. C
    Soft bones and deformities
  4. D
    Increased bone turnover
Question 45Single Answer
What is the primary pathophysiological mechanism in osteoporosis?
  1. A
    Increased bone resorption
  2. B
    Decreased bone resorption
  3. C
    Increased osteoblast activity
  4. D
    Excessive calcium deposition
Question 46Single Answer
Which of the following is a major risk factor for postmenopausal osteoporosis?
  1. A
    High testosterone levels
  2. B
    Increased estrogen levels
  3. C
    Estrogen deficiency
  4. D
    Hyperparathyroidism
Question 47Single Answer
Which diagnostic tool is considered the gold standard for diagnosing osteoporosis?
  1. A
    X-ray
  2. B
    Bone scintigraphy
  3. C
    Dual-energy X-ray absorptiometry (DEXA)
  4. D
    Serum calcium levels
Question 48Single Answer
What T-score on DEXA scan confirms osteoporosis?
  1. A
    -1.0 to +1.0
  2. B
    -1.0 to -2.5
  3. C
    ≤ -2.5
  4. D
    ≥ -1.0
Question 49Single Answer
Which of the following drugs is NOT used in osteoporosis management?
  1. A
    Bisphosphonates
  2. B
    Teriparatide
  3. C
    Denosumab
  4. D
    Methotrexate
Question 50Single Answer
Which of the following is a contraindication to bisphosphonate therapy?
  1. A
    Osteoarthritis
  2. B
    Esophageal stricture
  3. C
    Hypertension
  4. D
    Vitamin D deficiency
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