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Latest CISF ASI Paramedical Staff Exam Question (Objective Questions), MCQ in English

Subjects : Concerned Subject (Pharmacist)

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Concerned Subject (Pharmacist)

Question 1Single Answer
Which preparation is used to help prevent dehydration or achieve rehydration?
  1. A
    Lytren solution
  2. B
    Liposul
  3. C
    Bicytra
  4. D
    Mylicon
Question 2Single Answer
Emulsions prepared using Tweens as the principal emulsifying agents are usually of which type?
  1. A
    Water-in-oil
  2. B
    Oil-in-water
  3. C
    Multiple emulsion
  4. D
    Microcapsule dispersion
  5. E
    Β reversible
Question 3Single Answer
Compared with the corresponding crystalline form, an amorphous form of a drug is generally?
  1. A
    Less soluble
  2. B
    More soluble
  3. C
    Chemically identical to a solvate
  4. D
    Completely insoluble
Question 4Single Answer
A triple-roller mill is particularly useful in pharmaceutical preparation for reducing particle size and producing smooth?
  1. A
    Ointments
  2. B
    Hard gelatin capsules
  3. C
    Aerosols
  4. D
    Suppository molds
Question 5Single Answer
Particle-size reduction is most likely to improve drug absorption when absorption is limited primarily by which process?
  1. A
    Dissolution of a poorly soluble drug
  2. B
    Renal filtration
  3. C
    Hepatic metabolism
  4. D
    Plasma-protein synthesis
Question 6Single Answer
A material whose apparent viscosity increases as shear rate increases is classified as?
  1. A
    Dilatant
  2. B
    Newtonian
  3. C
    Pseudoplastic
  4. D
    Thixotropic
Question 7Single Answer
A solution contains 3 grains of a drug per US fluid ounce. Approximately what is its percentage strength w/v?
  1. A
    0.66%
  2. B
    0.20%
  3. C
    1.50%
  4. D
    6.60%
Question 8Single Answer
Cyanocobalamin is which type of substance?
  1. A
    Steroid
  2. B
    Vitamin
  3. C
    Cholinesterase inhibitor
  4. D
    Enzyme
Question 9Single Answer
Tweens are best classified as which type of pharmaceutical excipient?
  1. A
    Nonionic surfactants
  2. B
    Phospholipids
  3. C
    Glycosides
  4. D
    Inorganic electrolytes
Question 10Single Answer
Which process can promote separation of an emulsion by accelerating movement of dispersed droplets?
  1. A
    Centrifugation
  2. B
    Buffering
  3. C
    Isotonization
  4. D
    Sweetening
Question 11Single Answer
Creaming is a ________ process.
  1. A
    Reversible
  2. B
    Irreversible
  3. C
    Downward
  4. D
    Both (a) and (c)
Question 12Single Answer
o/w emulsions normally cream in _______ direction.
  1. A
    Downward
  2. B
    Upward
  3. C
    First up and then down
  4. D
    First down then up
Question 13Single Answer
Β ______ is an example of non-ionic polymer.
  1. A
    Cellulose
  2. B
    Pectin
  3. C
    Glucose
  4. D
    Methyl cellulose
Question 14Single Answer
Electrolytes are added in suspensions to _____ the zeta potential.
  1. A
    Neutralize
  2. B
    Decrease
  3. C
    Increase
  4. D
    Stabilize
Question 15Single Answer
The sedimentation volume of an ideal suspension should be _____
Β 
  1. A
    One
  2. B
    Greater than one
  3. C
    Zero
  4. D
    Less than one
Question 16Single Answer
Which combination correctly describes a flocculated pharmaceutical suspension?
  1. A
    Particles form loose aggregates and the supernatant becomes clear
  2. B
    Particles form a compact hard cake and the supernatant remains turbid
  3. C
    Sedimentation is negligible and particles remain completely dispersed
  4. D
    Redispersion becomes progressively impossible
Question 17Single Answer
Which law is commonly used to describe the sedimentation velocity of spherical particles in a dilute pharmaceutical suspension?
  1. A
    Stokes' law
  2. B
    Henry's law
  3. C
    Raoult's law
  4. D
    Beer-Lambert law
Question 18Single Answer
According to the phase-volume concept, approximately what maximum volume fraction of monodisperse spherical droplets corresponds to close packing before severe instability becomes likely?
  1. A
    0.26
  2. B
    0.50
  3. C
    0.74
  4. D
    0.90
Question 19Single Answer
Which among the following is the chief ingredient of anti-diarrhoeal mixture?
  1. A
    Charcoal
  2. B
    Kaolin
  3. C
    Calamine
  4. D
    Aluminum Hydroxide
Question 20Single Answer
Which rheological test applies a constant stress and measures time-dependent deformation of a semisolid material?
  1. A
    Creep test
  2. B
    Pycnometry
  3. C
    Nephelometry
  4. D
    Refractometry
Question 21Single Answer
Compared with its continuous aqueous phase, the apparent viscosity of an oil-in-water emulsion is generally?
  1. A
    Higher
  2. B
    Always lower
  3. C
    Exactly identical
  4. D
    Always zero
Question 22Single Answer
According to Stoke's equation, the creaming of emulsion will take place in _____ direction, if the density of the dispersed phase is more than that of the dispersion medium.
Β 
Β 
  1. A
    Downward
  2. B
    Upward
  3. C
    Centre
  4. D
    Both (a) and (b)
Question 23Single Answer
____ of an emulsion occurs when the distributionsΒ  is of globules is not uniform.
  1. A
    Caking
  2. B
    Breaking
  3. C
    Creaming
  4. D
    Coalescence
Question 24Single Answer
The commercial method for the preparation of emulsions is ______
Β 
  1. A
    Homogenization
  2. B
    Lyophilization
  3. C
    Centrifugation
  4. D
    Both (a) and (c)
Question 25Single Answer
According to Stokes' law, which change most directly reduces the rate of creaming in an emulsion?
  1. A
    Decreasing globule size
  2. B
    Increasing globule size
  3. C
    Decreasing continuous-phase viscosity
  4. D
    Increasing the density difference between phases
Question 26Single Answer
The ratio of oil : water : gum, used for the preparation of a primary emulsion containing a fixed oil is ____
  1. A
    4 : 4 : 2
  2. B
    4 : 2 : 1
  3. C
    1 : 2 : 4
  4. D
    2 : 4 : 4
Question 27Single Answer
The percentage of sucrose in simple syrup I.P is ___
  1. A
    66.7% w/w
  2. B
    85% w/w
  3. C
    56% w/w
  4. D
    33% w/w
Question 28Single Answer
Commonly used solvent in throat paint is ____
  1. A
    Castor Oil
  2. B
    Sucrose Syrup
  3. C
    Glycerin
  4. D
    Alcohol
Question 29Single Answer
Lugol's solution is an aqueous solution containing iodine together with which substance to enhance iodine solubility?
  1. A
    Potassium iodide
  2. B
    Sodium bicarbonate
  3. C
    Calcium chloride
  4. D
    Magnesium sulfate
Question 30Single Answer
Which of the following processes is used for the extraction of volatile oils from plants?
  1. A
    Simple Distillation
  2. B
    Steam Distillation
  3. C
    Extraction
  4. D
    Soxhlation
Question 31Single Answer
In atherosclerosis, the serum level of____decreases.
  1. A
    Triglycerides
  2. B
    VLDL
  3. C
    HDL
  4. D
    LDL
Question 32Single Answer
Which drug can significantly increase plasma digoxin concentrations and thereby increase the risk of digitalis toxicity?
  1. A
    Quinidine
  2. B
    Potassium chloride
  3. C
    Lidocaine
  4. D
    Magnesium sulfate
Question 33Single Answer
When quinidine is initiated in a patient receiving digoxin, which measure is particularly important?
  1. A
    Monitor digoxin concentration and adjust its dose when necessary
  2. B
    Routinely double the digoxin dose
  3. C
    Discontinue all potassium intake
  4. D
    Administer digoxin only intramuscularly
Question 34Single Answer
Name a substitute of enalapril.
  1. A
    Losartan
  2. B
    Rosiglitazone
  3. C
    Omeprazole
  4. D
    Famotidine
Question 35Single Answer
Antihypertensive drugsΒ Β Β Β Β Β Β Β Β Β Β Β Β  Β  Β  Β  Β  Β  Β  Β  Β  Β Β  Mode of action
1. MethyldopaΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  Β Β Β Β Β Β Β Β Β Β Β  (A) Ganglion blocker
2. HydralazineΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  Β Β Β Β Β Β Β Β Β Β Β  (B) Depletion of catecholamines
3. ReserpineΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  Β Β Β Β Β Β Β Β Β Β Β  (C) Direct action on arterioles
4. MecamylamineΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  Β Β Β Β Β Β Β Β Β Β Β  (D) False neurotransmitter
  1. A
    1-D, 2-C, 3-B, 4-A
  2. B
    1-A, 2-C, 3-D, 4-B
  3. C
    1-B, 2-A, 3-D, 4-C
  4. D
    1-A, 2-B, 3-C, 4-D
Question 36Single Answer
Match the cardiovascular drug with its principal pharmacological action:
1. Papaverine – Vasodilator
2. Verapamil – Calcium-channel blocker
3. Hydralazine – Direct arteriolar vasodilator
4. Dobutamine – β₁-adrenergic agonist
Which matching sequence is correct?
  1. A
    1, 2, 3 and 4 are correctly matched
  2. B
    Only 1 and 2 are correctly matched
  3. C
    Only 2 and 3 are correctly matched
  4. D
    Only 3 and 4 are correctly matched
Question 37Single Answer
Which of the following are the potential targets for designing antihypertensive drugs?
(A) H2-receptors
(B) Proton pump
(C) Β - adrenergic receptors
(D) Calcium channel proteins
  1. A
    A and B
  2. B
    C and D
  3. C
    B and D
  4. D
    A and D
Question 38Single Answer
Hypotensive agentsΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  Β  Β  Β  Β  Β Β  Β Β  Mode of action
1. ClonidineΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  (A) Direct action on blood vessels
2. CaptoprilΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  (B) - adrenoceptor antagonist
3. PrazosinΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  (C) Decreases sympathetic activity through brain
4. MinoxidilΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β  (D) Angiotensin converting enzyme inhibitor
  1. A
    1-A, 2-B, 3-C, 4-D
  2. B
    1-D, 2-C, 3-A, 4-B
  3. C
    1-C, 2-B, 3-D, 4-A
  4. D
    1-C 2-D, 3-B, 4-A
Question 39Single Answer
Which statement about digoxin is correct?
  1. A
    Its elimination half-life in adults with normal renal function is approximately 36–48 hours
  2. B
    It is metabolized almost completely by the liver
  3. C
    It primarily accelerates AV nodal conduction
  4. D
    Its principal elimination pathway is pulmonary excretion
Question 40Single Answer
Digitalis glycosides are used in congestive heart failure as they increase the____.
  1. A
    Force of myocardial contraction
  2. B
    Cardiac filling pressure
  3. C
    Heart rate
  4. D
    Venous pressure
Question 41Single Answer
Digitalis is used in congestive heart failure. It acts by ____.
  1. A
    Decreasing the intracellular sodium levels
  2. B
    Activating adenylyl cyclase to produce cAMP
  3. C
    Decreasing the release of calcium from sarcoplasmic reticulum
  4. D
    Inhibiting the action of Na+ -K+ -ATPase enzyme
Question 42Single Answer
Concomitant administration of ____ increases the risk of digitalis toxicity.
  1. A
    Lidocaine
  2. B
    Triamterene
  3. C
    Hydrochlorothiazide
  4. D
    Captopril
Question 43Single Answer
___is a cardioselective -blocker with vasodilatory action.
  1. A
    Atenolol
  2. B
    Bisoprolol
  3. C
    Nebivolol
  4. D
    Pindolol
Question 44Single Answer
___is specifically indicated for the treatment of supraventricular tachyarrhythmias.
  1. A
    Mexiletine
  2. B
    Diltiazem
  3. C
    Propranolol
  4. D
    Nifedipine
Question 45Single Answer
Which angiotensin-II receptor blocker is used in hypertension?
  1. A
    Valsartan
  2. B
    Amlodipine
  3. C
    Atenolol
  4. D
    Enalapril
Question 46Single Answer
When was the Pharmacy Act 1948 enacted ?
  1. A
    1945
  2. B
    1948
  3. C
    1950
  4. D
    1955
Question 47Single Answer
The Pharmacy Act 1948 regulates the profession of :
  1. A
    Medicine
  2. B
    Law
  3. C
    Pharmacy
  4. D
    Engineering
Question 48Single Answer
What term describes the study of how drugs affect the body and how the body affects drugs ?
  1. A
    Pathology
  2. B
    Physiology
  3. C
    Pharmacology
  4. D
    Histology
Question 49Single Answer
Which phase of drug development involves testing a new drug on healthy volunteers to determine its safety and dosage range ?
  1. A
    Phase I
  2. B
    Phase II
  3. C
    Phase III
  4. D
    Phase IV
Question 50Single Answer
Which route of drug administration provides the fastest onset of action ?
  1. A
    Oral
  2. B
    Intravenous
  3. C
    Subcutaneous
  4. D
    Topical
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