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Question for GATE Biotechnology Engineering - Quiz / Questions / MCQ in English

Last Update on : October 11, 2026

Duration: 180 ยท Questions: 65 ยท Max Marks: 65

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Latest GATE Biotechnology Engineering Exam Question (Objective Questions), MCQ in English

Subjects : General Aptitude, Engineering Mathematics, Biotechnology

Question Bank GATE Biotechnology Engineering Exam (Only MCQ) - English

General Aptitude

Q 1 :
Inhaling the smoke from a burning _____ could _____ you quickly.
  1. A.tire/tier
  2. B.tire/tyre
  3. C.tyre/tire
  4. D.tyre/tier
Q 2 :
Rice, a versatile and inexpensive source of carbohydrate, is a critical component of diet worldwide. Climate change, causing extreme weather, poses a threat to sustained availability of rice. Scientists are working on developing Green Super Rice (GSR), which is resilient under extreme weather conditions yet gives higher yields sustainably.
Which one of the following is the CORRECT logical inference based on the information given in the above passage ?
  1. A.GSR is an alternative to regular rice, but it grows only in an extreme weather
  2. B.GSR be used in future in response to adverse effects of climate change
  3. C.GSR grows in an extreme weather, but the quantity of produce is lesser than regular rice
  4. D.Regular rice will continue to provide good yields even in extreme weather
Q 3 :
The cost price of 20 articles is the same as the selling price of x articles. If the profit is 25%, then the value of x is :
  1. A.15
  2. B.16
  3. C.18
  4. D.25
Q 4 :
Pipes P and Q can fill a storage tank full of water in 10 and 6 minutes, respectively. Pipe R draws the water out from the storage tank at a rate of 34 litres per minute. P, Q and R operate at a constant rate. If it takes one hour to completely empty a full storage tank with all the pipes operating simultaneously, what is the capacity of the storage tank (in litres) ? 
  1. A.26.8 
  2. B.60.0 
  3. C.120.0
  4. D.127.5
Q 5 :
Choose the grammatically correct sentence?
  1. A.Neither of the robots are functioning properly
  2. B.Neither robots is functioning properly
  3. C.Neither of the robot are functioning properly
  4. D.Neither of the robots is functioning properly

Engineering Mathematics

Q 6 :
Consider the following expression :
where z, y, and t are variables, and   is a complex number. The partial differential equation derived from the above expression is
    Q 7 :
    For the equation
    the correct description is
    1. A.
      an ordinary differential equation of order 3 and degree 2 
    2. B.
      an ordinary differential equation of order 3 and degree 3 
    3. C.
      an ordinary differential equation of order 2 and degree 3 
    4. D.an ordinary differential equation of order 3 and degree รขโ‚ฌโ€น
    Q 8 :
    The value of (1 + i)12, where รขโ‚ฌโ€น , is.
    1. A.
      – 64 i 
    2. B.
      64 i
    3. C.64 
    4. D.– 64
    Q 9 :
    If (A=\begin{bmatrix}1&2\3&4\end{bmatrix}), what is (\det(A))?
    1. A.2
    2. B.(-2)
    3. C.5
    4. D.10
    Q 10 :
    If (A) is a (3\times3) matrix with (\det(A)=5), what is (\det(2A))?
    1. A.10
    2. B.40
    3. C.20
    4. D.80

    Biotechnology

    Q 11 :
    Which bond primarily links amino acids in a polypeptide chain?
    1. A.Peptide bond
    2. B.Glycosidic bond
    3. C.Phosphodiester bond
    4. D.Hydrogen bond
    Q 12 :
    The peptide bond has partial double-bond character primarily because of:
    1. A.Ionic interaction
    2. B.Van der Waals forces
    3. C.Hydrophobic interaction
    4. D.Resonance
    Q 13 :
    Which amino acid lacks a chiral carbon atom?
    1. A.Glycine
    2. B.Valine
    3. C.Alanine
    4. D.Serine
    Q 14 :
    Which amino acid contains an imidazole side chain?
    1. A.Arginine
    2. B.Histidine
    3. C.Lysine
    4. D.Tryptophan
    Q 15 :
    Disulfide bonds in proteins are formed between residues of:
    1. A.Methionine
    2. B.Serine
    3. C.Cysteine
    4. D.Threonine
    Q 16 :
    Which amino acid often disrupts an ฮฑ-helix because of its rigid cyclic structure?
    1. A.Alanine
    2. B.Leucine
    3. C.Proline
    4. D.Glutamate
    Q 17 :
    The ฮฑ-helix of proteins is stabilized mainly by hydrogen bonds between:
    1. A.Backbone C=O and N-H groups
    2. B.Adjacent amino acids
    3. C.Side chains only
    4. D.Terminal amino acids
    Q 18 :
    ฮฒ-sheets may consist of polypeptide strands arranged in:
    1. A.Parallel or antiparallel orientation
    2. B.Antiparallel orientation only
    3. C.Parallel orientation only
    4. D.Circular orientation only
    Q 19 :
    The tertiary structure of a globular protein refers primarily to:
    1. A.Overall three-dimensional folding of one polypeptide
    2. B.Local ฮฑ-helical structure
    3. C.Amino acid sequence
    4. D.Association of multiple chromosomes
    Q 20 :
    Quaternary structure is present in proteins that:
    1. A.Contain only ฮฑ-helices
    2. B.Lack peptide bonds
    3. C.Have more than one polypeptide subunit
    4. D.Are always enzymes
    Q 21 :
    Protein denaturation generally does NOT disrupt:
    1. A.Primary peptide-bond sequence
    2. B.Hydrophobic interactions
    3. C.Hydrogen bonds
    4. D.Ionic interactions
    Q 22 :
    Molecular chaperones primarily assist in:
    1. A.Protein folding
    2. B.DNA replication
    3. C.Lipid digestion
    4. D.ATP hydrolysis only
    Q 23 :
    Which protein is composed of four polypeptide subunits in adult humans?
    1. A.Hemoglobin
    2. B.Myoglobin
    3. C.Ribonuclease A
    4. D.Lysozyme
    Q 24 :
    Myoglobin differs from hemoglobin in that myoglobin:
    1. A.Is a tetramer
    2. B.Shows strong cooperative oxygen binding
    3. C.Is monomeric
    4. D.Contains no heme
    Q 25 :
    Cooperative binding of oxygen by hemoglobin produces a:
    1. A.Linear binding curve
    2. B.Hyperbolic curve identical to myoglobin
    3. C.Sigmoidal binding curve
    4. D.Constant-rate curve
    Q 26 :
    A positive Bohr effect means that decreasing pH generally:
    1. A.Increases hemoglobin affinity for oxygen
    2. B.Decreases hemoglobin affinity for oxygen
    3. C.Eliminates heme groups
    4. D.Prevents carbon dioxide transport
    Q 27 :
    The predominant linkage joining glucose units in glycogen chains is:
    1. A.ฮฒ(1โ†’4)
    2. B.ฮฒ(1โ†’6)
    3. C.ฮฑ(1โ†’4)
    4. D.ฮฑ(1โ†’2)
    Q 28 :
    Branch points in glycogen contain:
    1. A.ฮฒ(1โ†’4) linkages
    2. B.ฮฑ(1โ†’6) linkages
    3. C.ฮฑ(1โ†’2) linkages
    4. D.ฮฒ(1โ†’6) linkages exclusively
    Q 29 :
    Cellulose is a polymer of glucose joined principally through:
    1. A.ฮฒ(1โ†’4) bonds
    2. B.ฮฑ(1โ†’4) bonds
    3. C.ฮฑ(1โ†’6) bonds
    4. D.ฮฑ(1โ†’2) bonds
    Q 30 :
    Lactose is composed of:
    1. A.Glucose and fructose
    2. B.Glucose and galactose
    3. C.Fructose and galactose
    4. D.Two fructose molecules
    Q 31 :
    Sucrose is composed of:
    1. A.Glucose and galactose
    2. B.Glucose and fructose
    3. C.Two glucose molecules
    4. D.Ribose and glucose
    Q 32 :
    Which is a reducing disaccharide?
    1. A.Sucrose
    2. B.Lactose
    3. C.Trehalose
    4. D.Neither lactose nor maltose
    Q 33 :
    The pentose sugar present in RNA is:
    1. A.Glucose
    2. B.Ribulose
    3. C.Ribose
    4. D.Deoxyribose
    Q 34 :
    DNA contains which pyrimidine that is normally absent from RNA?
    1. A.Cytosine
    2. B.Uracil
    3. C.Thymine
    4. D.Guanine
    Q 35 :
    A phosphodiester bond in nucleic acids connects:
    1. A.Two nitrogenous bases
    2. B.Sugar directly to a protein
    3. C.Adjacent sugar residues through phosphate
    4. D.Two phosphate groups only
    Q 36 :
    Adenine forms Watson-Crick base pairs with thymine through:
    1. A.Two hydrogen bonds
    2. B.One hydrogen bond
    3. C.Three hydrogen bonds
    4. D.Four hydrogen bonds
    Q 37 :
    Guanine pairs with cytosine through:
    1. A.One hydrogen bond
    2. B.Three hydrogen bonds
    3. C.Two hydrogen bonds
    4. D.Four hydrogen bonds
    Q 38 :
    The major driving force stabilizing the interior of many globular proteins is:
    1. A.Covalent DNA bonding
    2. B.Hydrophobic interaction
    3. C.Glycosidic linkage
    4. D.Phosphorylation
    Q 39 :
    Phospholipids are amphipathic because they contain:
    1. A.Both hydrophilic and hydrophobic regions
    2. B.Only charged groups
    3. C.Only hydrophobic groups
    4. D.Only carbohydrate residues
    Q 40 :
    Cholesterol in animal cell membranes generally:
    1. A.Eliminates membrane proteins
    2. B.Forms cellulose fibers
    3. C.Hydrolyzes phospholipids
    4. D.Modulates membrane fluidity
    Q 41 :
    Triacylglycerols primarily function as:
    1. A.Genetic material
    2. B.Membrane ion channels
    3. C.Enzymatic cofactors
    4. D.Long-term energy stores
    Q 42 :
    Saturated fatty acids contain:
    1. A.No carbon-carbon double bonds
    2. B.One or more C=C bonds
    3. C.Only triple bonds
    4. D.Phosphate groups in every molecule
    Q 43 :
    Cis double bonds in fatty acids generally:
    1. A.Make chains straighter
    2. B.Introduce kinks into hydrocarbon chains
    3. C.Convert lipids to proteins
    4. D.Increase peptide bonding
    Q 44 :
    The major storage carbohydrate in animals is:
    1. A.Cellulose
    2. B.Starch
    3. C.Glycogen
    4. D.Chitin
    Q 45 :
    Chitin contains repeating units derived from:
    1. A.Fructose
    2. B.Galactose
    3. C.N-acetylglucosamine
    4. D.Ribose
    Q 46 :
    The pH at which an amino acid has zero net charge is its:
    1. A.Km
    2. B.pKa only
    3. C.Vmax
    4. D.Isoelectric point
    Q 47 :
    At physiological pH, lysine side chains are generally:
    1. A.Positively charged
    2. B.Negatively charged
    3. C.Uncharged aromatic groups
    4. D.Covalently phosphorylated
    Q 48 :
    Aspartate and glutamate generally possess side chains that are:
    1. A.Positively charged
    2. B.Aromatic and neutral
    3. C.Negatively charged at physiological pH
    4. D.Sulfur containing
    Q 49 :
    Which amino acid has an aromatic indole side chain?
    1. A.Histidine
    2. B.Tyrosine
    3. C.Phenylalanine
    4. D.Tryptophan
    Q 50 :
    The purine bases in nucleic acids are:
    1. A.Adenine and guanine
    2. B.Cytosine and thymine
    3. C.Uracil and thymine
    4. D.Cytosine and uracil

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