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Latest GSSSB Junior Pharmacist Exam Question (Objective Questions), MCQ in English

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Pharmacist

Question 1Single Answer
Which preparation is used to help prevent dehydration or achieve rehydration?
  1. ALytren solution
  2. BLiposul
  3. CBicytra
  4. DMylicon
Question 2Single Answer
Emulsions prepared using Tweens as the principal emulsifying agents are usually of which type?
  1. AWater-in-oil
  2. BOil-in-water
  3. CMultiple emulsion
  4. DMicrocapsule dispersion
  5. E reversible
Question 3Single Answer
Compared with the corresponding crystalline form, an amorphous form of a drug is generally?
  1. ALess soluble
  2. BMore soluble
  3. CChemically identical to a solvate
  4. DCompletely insoluble
Question 4Single Answer
A triple-roller mill is particularly useful in pharmaceutical preparation for reducing particle size and producing smooth?
  1. AOintments
  2. BHard gelatin capsules
  3. CAerosols
  4. DSuppository molds
Question 5Single Answer
Particle-size reduction is most likely to improve drug absorption when absorption is limited primarily by which process?
  1. ADissolution of a poorly soluble drug
  2. BRenal filtration
  3. CHepatic metabolism
  4. DPlasma-protein synthesis
Question 6Single Answer
A material whose apparent viscosity increases as shear rate increases is classified as?
  1. ADilatant
  2. BNewtonian
  3. CPseudoplastic
  4. DThixotropic
Question 7Single Answer
A solution contains 3 grains of a drug per US fluid ounce. Approximately what is its percentage strength w/v?
  1. A0.66%
  2. B0.20%
  3. C1.50%
  4. D6.60%
Question 8Single Answer
Cyanocobalamin is which type of substance?
  1. ASteroid
  2. BVitamin
  3. CCholinesterase inhibitor
  4. DEnzyme
Question 9Single Answer
Tweens are best classified as which type of pharmaceutical excipient?
  1. ANonionic surfactants
  2. BPhospholipids
  3. CGlycosides
  4. DInorganic electrolytes
Question 10Single Answer
Which process can promote separation of an emulsion by accelerating movement of dispersed droplets?
  1. ACentrifugation
  2. BBuffering
  3. CIsotonization
  4. DSweetening
Question 11Single Answer
Which gastrointestinal effect is characteristically associated with oral iron preparations?
  1. ADarkening of stools
  2. BBlue discoloration of saliva
  3. CGreen discoloration of tears
  4. DPurple discoloration of sweat
Question 12Single Answer
Orally administered lidocaine has limited systemic usefulness largely because it undergoes extensive?
  1. AFirst-pass hepatic metabolism
  2. BRenal tubular secretion before absorption
  3. CPhotochemical degradation in the stomach
  4. DPulmonary metabolism before absorption
Question 13Single Answer
On exposure to air and light, phenol may gradually develop which discoloration because of oxidation?
  1. APink to reddish coloration
  2. BBright green coloration
  3. CDeep blue coloration
  4. DPure white coloration
Question 14Single Answer
Approximately how much HgCl₂ is required to prepare 1 US pint (about 473 mL) of a 1:5000 w/v solution?
  1. A9.5 mg
  2. B47.3 mg
  3. C94.6 mg
  4. D473 mg
Question 15Single Answer
Which sulfonylurea has historically been associated with potentiation of the antidiuretic action of vasopressin?
  1. AChlorpropamide
  2. BChloramphenicol
  3. CPhenytoin
  4. DDicoumarol
Question 16Single Answer
Which two drug properties are commonly altered by pharmaceutical complexation?
  1. AStability and solubility
  2. BAtomic number and density
  3. CMolecular formula and atomic mass
  4. DRadioactivity and isotopic abundance
Question 17Single Answer
If drug distribution into tissues occurs more slowly than elimination from plasma, what is most likely to occur initially?
  1. AFailure to rapidly attain distribution equilibrium
  2. BImmediate pharmacodynamic tolerance
  3. CComplete inhibition of metabolism
  4. DIrreversible plasma-protein binding
Question 18Single Answer
In pharmaceutical aerosol terminology, PSIG stands for?
  1. APounds per square inch gauge
  2. BPressure standard in glass
  3. CPounds per square inch gravity
  4. DPropellant strength in grams
Question 19Single Answer
In the older terminology of radiation protection, the abbreviation rem stands for?
  1. ARoentgen equivalent man
  2. BRadiation emission meter
  3. CRelative electron mass
  4. DRoentgen exposure measurement
Question 20Single Answer
Azathioprine is primarily classified as a?
  1. AImmunosuppressant
  2. BCardiotonic
  3. CAntacid
  4. DLocal anesthetic
Question 21Single Answer
Creaming is a ________ process.
  1. AReversible​
  2. BIrreversible
  3. CDownward
  4. DBoth (a) and (c)
Question 22Single Answer
o/w emulsions normally cream in _______ direction.
  1. ADownward
  2. BUpward
  3. CFirst up and then down
  4. DFirst down then up
Question 23Single Answer
 ______ is an example of non-ionic polymer.
  1. ACellulose
  2. BPectin
  3. CGlucose
  4. DMethyl cellulose
Question 24Single Answer
Electrolytes are added in suspensions to _____ the zeta potential.
  1. ANeutralize
  2. BDecrease
  3. CIncrease
  4. DStabilize
Question 25Single Answer
The sedimentation volume of an ideal suspension should be _____
 
  1. AOne
  2. BGreater than one
  3. CZero
  4. DLess than one
Question 26Single Answer
Which combination correctly describes a flocculated pharmaceutical suspension?
  1. AParticles form loose aggregates and the supernatant becomes clear
  2. BParticles form a compact hard cake and the supernatant remains turbid
  3. CSedimentation is negligible and particles remain completely dispersed
  4. DRedispersion becomes progressively impossible
Question 27Single Answer
Which law is commonly used to describe the sedimentation velocity of spherical particles in a dilute pharmaceutical suspension?
  1. AStokes' law
  2. BHenry's law
  3. CRaoult's law
  4. DBeer-Lambert law
Question 28Single Answer
According to the phase-volume concept, approximately what maximum volume fraction of monodisperse spherical droplets corresponds to close packing before severe instability becomes likely?
  1. A0.26
  2. B0.50
  3. C0.74
  4. D0.90
Question 29Single Answer
Which among the following is the chief ingredient of anti-diarrhoeal mixture?
  1. ACharcoal
  2. BKaolin
  3. CCalamine
  4. DAluminum Hydroxide
Question 30Single Answer
Which rheological test applies a constant stress and measures time-dependent deformation of a semisolid material?
  1. ACreep test
  2. BPycnometry
  3. CNephelometry
  4. DRefractometry
Question 31Single Answer
Compared with its continuous aqueous phase, the apparent viscosity of an oil-in-water emulsion is generally?
  1. AHigher
  2. BAlways lower
  3. CExactly identical
  4. DAlways zero
Question 32Single Answer
According to Stoke's equation, the creaming of emulsion will take place in _____ direction, if the density of the dispersed phase is more than that of the dispersion medium.
 
 
  1. ADownward
  2. BUpward
  3. CCentre
  4. DBoth (a) and (b)
Question 33Single Answer
____ of an emulsion occurs when the distributions  is of globules is not uniform.
  1. ACaking
  2. BBreaking
  3. CCreaming
  4. DCoalescence
Question 34Single Answer
The commercial method for the preparation of emulsions is ______
 
  1. AHomogenization
  2. BLyophilization
  3. CCentrifugation
  4. DBoth (a) and (c)
Question 35Single Answer
According to Stokes' law, which change most directly reduces the rate of creaming in an emulsion?
  1. ADecreasing globule size
  2. BIncreasing globule size
  3. CDecreasing continuous-phase viscosity
  4. DIncreasing the density difference between phases
Question 36Single Answer
The ratio of oil : water : gum, used for the preparation of a primary emulsion containing a fixed oil is ____
  1. A4 : 4 : 2
  2. B4 : 2 : 1
  3. C1 : 2 : 4
  4. D2 : 4 : 4
Question 37Single Answer
The percentage of sucrose in simple syrup I.P is ___
 
 
  1. A66.7% w/w
  2. B85% w/w
  3. C56% w/w
  4. D33% w/w
Question 38Single Answer
Commonly used solvent in throat paint is ____
  1. ACastor Oil
  2. BSucrose Syrup
  3. CGlycerin
  4. DAlcohol
Question 39Single Answer
Lugol's solution is an aqueous solution containing iodine together with which substance to enhance iodine solubility?
  1. APotassium iodide
  2. BSodium bicarbonate
  3. CCalcium chloride
  4. DMagnesium sulfate
Question 40Single Answer
Which of the following processes is used for the extraction of volatile oils from plants?
  1. ASimple Distillation
  2. BSteam Distillation
  3. CExtraction
  4. DSoxhlation
Question 41Single Answer
In atherosclerosis, the serum level of____decreases.
  1. ATriglycerides
  2. BVLDL
  3. CHDL
  4. DLDL
Question 42Single Answer
Which drug can significantly increase plasma digoxin concentrations and thereby increase the risk of digitalis toxicity?
  1. AQuinidine
  2. BPotassium chloride
  3. CLidocaine
  4. DMagnesium sulfate
Question 43Single Answer
When quinidine is initiated in a patient receiving digoxin, which measure is particularly important?
  1. AMonitor digoxin concentration and adjust its dose when necessary
  2. BRoutinely double the digoxin dose
  3. CDiscontinue all potassium intake
  4. DAdminister digoxin only intramuscularly
Question 44Single Answer
Name a substitute of enalapril.
  1. ALosartan
  2. BRosiglitazone
  3. COmeprazole
  4. DFamotidine
Question 45Single Answer
Antihypertensive drugs                                 Mode of action
1. Methyldopa                                               (A) Ganglion blocker
2. Hydralazine                                              (B) Depletion of catecholamines
3. Reserpine                                                 (C) Direct action on arterioles
4. Mecamylamine                                         (D) False neurotransmitter
  1. A1-D, 2-C, 3-B, 4-A
  2. B1-A, 2-C, 3-D, 4-B
  3. C1-B, 2-A, 3-D, 4-C
  4. D1-A, 2-B, 3-C, 4-D
Question 46Single Answer
Match the cardiovascular drug with its principal pharmacological action:
1. Papaverine – Vasodilator
2. Verapamil – Calcium-channel blocker
3. Hydralazine – Direct arteriolar vasodilator
4. Dobutamine – β₁-adrenergic agonist
Which matching sequence is correct?
  1. A1, 2, 3 and 4 are correctly matched
  2. BOnly 1 and 2 are correctly matched
  3. COnly 2 and 3 are correctly matched
  4. DOnly 3 and 4 are correctly matched
Question 47Single Answer
Which of the following are the potential targets for designing antihypertensive drugs?
(A) H2-receptors
(B) Proton pump
(C)  - adrenergic receptors
(D) Calcium channel proteins
  1. AA and B
  2. BC and D
  3. CB and D
  4. DA and D
Question 48Single Answer
Hypotensive agents                                Mode of action
1. Clonidine                                      (A) Direct action on blood vessels
2. Captopril                                        (B) - adrenoceptor antagonist
3. Prazosin                                        (C) Decreases sympathetic activity through brain
4. Minoxidil                                        (D) Angiotensin converting enzyme inhibitor
  1. A1-A, 2-B, 3-C, 4-D
  2. B1-D, 2-C, 3-A, 4-B
  3. C1-C, 2-B, 3-D, 4-A
  4. D1-C 2-D, 3-B, 4-A
Question 49Single Answer
Which statement about digoxin is correct?
  1. AIts elimination half-life in adults with normal renal function is approximately 36–48 hours
  2. BIt is metabolized almost completely by the liver
  3. CIt primarily accelerates AV nodal conduction
  4. DIts principal elimination pathway is pulmonary excretion
Question 50Single Answer
Digitalis glycosides are used in congestive heart failure as they increase the____.
  1. AForce of myocardial contraction
  2. BCardiac filling pressure
  3. CHeart rate
  4. DVenous pressure
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