The random errors associated with the measurement of P and Q are 10% and 2%, respectively. What is the percentage random error in P/Q?

In how many distinguishable ways can the letters of the word CHANCE be arranged?

Find out the missing pattern.

Seeds when soaked in water gain about 20% by weight and 10% by volume. By what factor does the density increase?

Retarding frictional force f on a moving ball, is proportional to it velocity, V. Two identical balls roll down identical slopes (A & B) from different heightsheights. Compare the retarding forces and the velocities of the balls at the bases of the slopes.

Two cockroaches of the same species have th’e same thickness but
different lengths and widths. Their ability to survive in oxygen deficient environments will be compromised if

The bar chart shows number of seats won by four political parties in a state legislative assembly.Which of the following pie-charts correctly depicts this information?

Intravenous (IV) fluid has to be administered to a child of 12 kg with dehydration, at a dose of 20 mg of fluid per kg of body weight, in 1hour. What should be the drip rate (in drops/min) of IV fluid? (1 mg = 20drops)

A hall with a high roof is supported by an array of identical columns such that, to a person lying on the floor and looking at the ceiling, the columns appear parallel to each other. Which of the following designs conforms to this?

Which of the following graphs correctly shows the speed and the corresponding distance covered by an object moving along a straight line? _  _  _  _ speed    _______distance

Choose the most appropriate pH at which the net charge is zero for the molecule from the data shown below :

Choose the correct statement about peptides in the Ramachandran plot.

Equilibrium constant (K'eq) of a reaction is a ratio of product to substrate concentrations. The relation between (K'eq) and free energy change in a reaction (G') is as follows 
G' = –RT ln K'eq
Reaction A and Reaction B have K'eq values of 10 and 100,respectively. Which of the following statements is correct with respect to G'?

Excess oxygen consumed after a vigorous exercise is

Which one of the following describes the primary function of flippases?

Mitotic cyclin-CDK activity peaks in M phase. This is because

The gel to liquid crystalline phase transition temperature in phosphatidyl choline (PC) lipids composed of dioleoyl (DO), dipal-mitoyl (DP), disteroyl (DS) and palmitoyl ol.eoyl (PO) fatty acids in increasing order will bein increasing order will be

Which of the following is NOT an example of transmembrane transport between different subcellular compartments?

Which of the following are NOT transcribed by RNA polymerase II? 

RNA editing, a post-transcriptional process, is achieved with the help of guide RNA (g-RNA). Which one of the following statements about the process is NOT true?

Telomerase, a RNA-protein complex which completes the replication of telomeres during DNA synthesis, is a specialised

Consider a short double-stranded linear DNA molecule of 10 complete turns with 10.5 bp/ turn. The ends of the DNA molecule are sealed together to make a relaxed circle. This relaxed circle will have a linking number of

In the given signalling cascade, which one of the following molecules is denoted by ‘B’?

The secondary antibodies routinely used for the detection of primary antibodies in western blotting experiment are 

Which of the following events will NOT usually lead to transformation of a normal cell into a cancer cell? 

Which one of the following is a food borne toxin?

Which one of the following statements is WRONG?

Certain proteins of mRNAs that are regionally localized within the unfertilized egg and regulate development are called

Cell to cell communication is important in development of an organism. The ability of cells to respond to a specific inductive signal is called

Apical ectodermal ridge induction is essential for tetrapod limb development. Which one of the following is NOT essential for the formation of a functional limb? 

From the following statements
1. Hydrogen, Deuterium and Tritium differ in the number of protons.
2. Hydrogen, Deuterium and Tritium differ in the number of neutrons.
3. Both Deuterium and Tritium are radioactive and decay to Hydrogen and Deuterium, respectively.
4. Tritium is radioactive and decays to Helium.
5. Carbon-14 decays to Nitrogen-14.
6. Carbon-14 decays to Carbon-13.
Pick the combination with ALL correct statements. 

From the following statements,
1. For a reaction to occur spontaneously the free energy change must be negative.
2. The interaction between two nitrogen molecules in the gaseous state is predominantly electrostatic.    
3. By knowing bond energies, it is possible to deduce whether the bond is covalent bond or hydrogen bond.
4. Hydrophobic interactions are not important in a folded globular protein.
Pick the combination with ALL WRONG statements. 

The following are four statements on peptide/protein conformation :
1. Glycine has the largest area of con-formationally allowed space in the Ramachandran plot of f and Y
2. A 20-residue peptide that is acetylated at the N-terminus and amidated at the C-terminus has f = –60°(±5), Y = –30°(±5) for all the residues. It can be concluded that conformation of the peptide is helix-turn-strand.
3. The allowed values of f, Y for amino acids in a protein are not valid for short perptides.
4. A peptide Acetyl-A1-A2-A3-A4-CONH2 (A1-A4 are amino acids) adopts a well defined b-turn. The dihedral angles of A2 and A3 determine the type of b-turn.
 Choose the combination of correct statements. 

A researcher investigated a set of conditions for a protein with an isoelectric point of 6.5 and also binds to calcium. This protein was subjected to four independent treatments: (i) pH 6.4, (ii) 10% glycerol, (iii) 10 mM CaCl2, (iv) 40% ammonium sulphate. This was followed by centrifugation and estimation of the protein in the supernatant. The results are depicted in the graph below : Which of the following treatments best represents the results shown in the graph?

In the biosynthesis of purine :
 

A researcher was investigating the substrate specificity of two different enzymes, X and Y, on the same substrate. Both the enzymes were subjected to treatment with either heat or an inhibitor which inhibits the enzymes activity. Following are the results obtained where a = inhibitor treatment, b = heat treatment and c = control.  Which of the following statements is correct ?
 

In an experiment, red blood cells were subjected to lysis and any unbroken cells were removed by centrifugation at 600 g. The supernatant was taken and centrifuged at 100,000 g. The pellet was extracted with 5M NaCl and again centrifuged at 100,000 g. Which of the following proteins would be present in the supernatant?

In order to study the intracellular trafficking of protein ‘A’, it was tagged with GFP (A-GFP). Fluorescence microscopy showed that A-GFP co-localizes the LAMP1. In the presence of bafilomycin A, and inhibitor of H+-ATPase, A-GFP does not co-localize with LAMP1. Instead, it co-localizes with LC3 puncta. Which one of the following statements is TRUE? 

‘A’ is an inhibitor of chloroplast function. The production of O2, and the synthesis of ATP are measured in illuminated chloroplasts before and after addition of ‘A’ as shown below :Which statement is correct?

During cell cycle progression from G1 to S, cyclin D-CDK4 phosphorylates Rb and reduces its affinity for E2F, E2F dissociates from Rb and activates S-phase gene expression Over-expression of protein ‘A’ arrests G1 phase progression.Which of the following statements is TRUE?

Cells in S-phase of the cell cycle were fused to cells in the following stages of cell cycle: (a) G1 phase, (b) G2 phase; (c) M phase. These cells were then grown in mediam containing tritiated thymidine. Maximal amount of freshly labelled DNA is likely to be obtained in S-phase cells fused with : 

Addition of the antibiotic cephalexin to growing E. coli cells lead to fomentation of the cells, followed by lysis. Cephalexin is an inhibitor of:

Fluorescently tagged protein was used to study protein secretion in yeast. Fluorescence was observed in :
(a) the Golgi
(b) the secretory vesicles
(c) the rough ER
Which of the following describes best the sequence in which these events occur?

In order to ensure that only fully processed mature mRNAs are allowed to be exported to cytosol, pre-mRNAs associated with snRNPs are retained in the nucleus. To demonstrate this, an experiment was performed where a gene coding a pre-mRNA, with a single intron was mutated either at the 5’ or 3’ splice sites or both the splice site.Given below are a few possible outcomes:
1. Pre-mRNA having mutation at both the splice sites will be retained in the nucleus because of the presence of bound snRNPs.
2. Pre-mRNA having mutation at both the splice sites will be exported to cytosol because of the absence of bound snRNPs.
3. Pre-mRNA mutated at either 3' or 5' splice sites will be retained in the nucleus because of the presence of bound snRNPs.
4. Pre-mRNA mutated at either 3' or 5' splice sites will be exported to cytosol because of the absence of bound snRNPs.
 Choose the correct combination of possible outcomes :

Polysome profiling of cells treated with three hypothetical translation inhibitors is shown in the plot below. These three inhibitors are
1. CHP - leaky inhibitor of translation
2. LTM - arrests ribosome at the initiation codon
3. PTM - inhibits ribosome scanning
  
 Match the polysome profile to the inhibitor

In mammals CG rich sequences are usually methylated at C, which is a way for marking genes for silencing. Although the promoters of housekeeping genes are often associated with CpG islands yet they are expressed in mammals. 

Telomerase, a protein-RNA complex, has a special reverse transcriptase activity that completes replication of telomerase during DNA synthesis. Although it has many properties similar to DNA polymerase, some of them are also different. Which one of the following properties of telomerase is different from that of DNA polymerase?

In eukaryotes, a specific cyclin dependent kinase (CDK) activity is required for the activation of loaded helicases to initiate replication. On the contrary, this CDK activity inhibits the loading of helicases onto the origin of replication. Considering the fact that during each cycle, there is only one opportunity for helicases to be loaded on to origins and only one opportunity for these loaded helicases to be activated, which one of the following graphs best depicts this CDK activity in G1 and S phases of cell cycle?

In Trypanosomes, a 35 base leader sequence is joined with several different transcripts making functional mRNAs. The leader sequence is joined with the other RNAs by

Following are the list of some of the pathogens (column A) & the unique mechanisms they employ for invading the immune response (column B). Which of the following is the correct match between the organism and their respective mechanism to evade immune response?