Question for JK SET Life Science - Quiz / Questions / MCQ in English

In each of the following groups of words is a hidden number, based on which you should arrange them in ascending order. Pick the right answer :
1.   Tinsel event
2.   Man in England
3.  Good height
4.   Last encounter

Let m and n be two positive integers such that  m + n + mn = 118 , Then the value of  m + n is

AB  is the diameter of a circle. The chord CD is perpendicular to AB intersecting it at P. If CP = 2 and  PB = 1, the radius of the circle is  :

What is angle x in the schematic diagram given below  ?

From a group of 40 players,  a cricket team of 11 players is chose. The, one of the eleven is chose as the captain of the team. The total number of ways this can done is  [ below means the number of ways  n objects can be chosen from  m  objects ] 

Starting from a point  A you fly one mile south,  then one mile east, then one mile north which brings you back to point A. Point A is NOT the north Pole. Which of the following  MUST be true?

A 3 m long car goes past a 4 m long truck at rest on the road. The speed of the car is 7  m/s. The time taken to go past is  :

Jar W contains 40 white marble and jar B contains 40 black marbles. Ten black marbles from B are transferred to  W and mixed thoroughly. Now, ten randomly selected marbles from W are put back in Jar B to make  40 marbles in each jar. The number of black marbles in W :

Consider  3 parallel strips of  10 m width running around the Earth, parallel to the equator,  A₁ at the Equator,  A₂ at the Tropic of Cancer and A₃ at the Arctic Circle. The order of the areas of the strips is  :.

If  aN  ⇒  S
eF ⇒  1
gH ⇒> M
then  nS ⇒  ?

How many non - negative integers less than 10,000 are there such that the sum of the digits of the number is divisible by there  ?

Of three persons A,  B and  C  one always lies while the others always speak the truth. C asked A, " Do you always speak the truth, yes or no? " He said something that  C could not hear. So,  C asked B. " what did  A say " B replied,  " A  said  No ".   So,  who is the liar  ?

Two ants,  initially at diametrically opposite points  A and  B on a circular ring of radius R,  start crawling towards each other. The speed of the one at A is half of that of the one at  B. The point at which they meet is at a straight line distance of  :

Based on the graph,  which of the following statements is  NOT  true?

A pyramid shaped toy is made by tightly placing cubic blocks  of  1 x  1 x  1 cm³ . The base of the toy is a Square 4 x 4 cm² The width of   each step is 0.5 cm.  How many blocks are required to make the toy  ?

Information in DNA is in the from of sequence of 4 bases namely  A,  T,  G and  C. The proportion of G is the same as that of C, and than of A is the same as that of T. Which of the following strands of DNA will potentially have maximum diversity ( i. e.,  maximum information content per base)  ?

Two plane mirrors facing each other are kept at 60° to each other.  A point is located on the angle bisector. The number of images of the point is  :

I bought a shirt at  10% discount and sold it to a friend at a loss of 10% . If the friend paid me  Rs 729.00  for the shirt,  what was the undiscounted price of the shirt? 

A single celled spherical organism contains  70%  water by volume. If it loses  10%  of its water content,  how much would its surface area change by approximately?

Suppose :
1.    x =  4
2.   Then,  x -- 4 = x² - 4² ( as both sides are zero)
3.   Therefore,  ( x - 4) = ( x - 4 ) (x +  4) Cancelling (x-4)   from both sides
4.   1  =  (x + 4)
5.  The,  x  =  -  3
Which is the wrong step?

A 1% (w/v) solution of a sugar polymer is digested by an enzyme (20 𝜇g, MW = 200,000).The rate of monomer sugar  (MW = 400) liberated was determined to have a maximal initial velocity of  10 mg formed /min. The turnover number (min ^{- 1}) will be

In an alpha helical polypeptide,  the back bone hydrogen bonds are between

Following are three single stranded  DNA sequences that form secondary structures.
1.  A T T G A G C G A T C A A T
2.  A T T G A G C G A T A T C A A T
3.  A G G G A G C G A T C C C T
Based on their stability,  which one is correct  ?

What phenotype would you predict for a mutant mouse lacking one of the genes required for site-specific recombination in lymphocytes  ?

The key determinant of the plane of cytokinesis in mammalian cells is the position of

Beating of cilia is regulated by

Cystic fibrosis transmembrane conductance regulator  ( CFTR)  is known to control the transport of which ion? 

In bacteria, heat - shock response is Primarily controlled by

In type II splicing 

Given below are some statements about prokaryotic and eukaryotic mobile genetic elements or transposons.
1.  Most mobile genetic elements in bacteria transpose via an  RNA intermediate.
2.  Most mobile genetic elements in bacteria are  DNA.
3.  Mobile genetic elements in eukaryotes are only retrotransposons.
4.  Both,  RNA and  DNA  transposons,  are found in eukaryotrs.
Choose the correct combination.

Copying errors occurring during replication are corrected by the reading activity of  DNA  polymerases that recognize incorrect bases 

During each cycle of chain elongation in translation,  how many conformational changes does the ribosome undergo that are coupled to  GTP  hydrolysis? 

Collagens are the most abundant component of the extracellular matrix. In order to maintain normal physiological process like would healing, bone development, etc.,  which one of the following type of enzymes is  MOST important  ?

Which one of the following events  NEVER activates the G-protein coupled receptor for sequestering  Ca²⁺  release  ?

The main difference between normal and transformed cells are

When bacteria growing at 20⁰C are warmed at  37⁰C,  they are most likely to synthesize membrane lipids with more

Hydra shows morphallactic regeneration and involves which one of the following signal transduction pathway in its axis formation?

The mammalian oocyte prior to sperm entry is arrested at what stage of cell division?

The pluripotency of the inner cell mass in mammals is maintained by a core of three transcription factors namely, 

Which one of the following statements about LEAFY  (LFY),  a regulatory gene in Arabidopsis thaliaxa,  is correct  ?

The quantum yield of oxygen evolution during photosynthesis drastically drops in far-red light. This effect is known as  :

Dark-grown seedings display ' triple response ' when exposed to ethylene. Which one of the following is  NOT a part of ' triple response  '?

Which one of the following compounds is generally translocated in the phloem? 

Nitrogen gas is reduced to ammonia by nitrogen fixation method. In order to execute the process, which one of the following compounds in usually required?

The  S wave of normal human  ECG originates due to

Which one of the following skeletal muscles of human body contains highest number of muscle fiber in a motor unit? 

In which of the following conditions is Based Metabolic Rate  (BMR)  the lowest? 

Which one of the following combinations must be present in a steroid receptor that is located in the cytoplasm  ?

' Segregation of alleles can occur at Anaphase I or at Anaphase II  of meiosis '. With reference to this statement, which one of the following organism is an ideal model system for identifying stage of allelic segregation at meiosis  ?

Genes A,  B and  C control three phenotypes which assort independently. A plant with the genotype  Aa Bb Cc  is selfed. What is the probability for progeny which shows the dominant phenotype for  AT LEAST ONE  of the phenotypes contolled by genes  A,  B and  C? 

Hybrid dysgenesis in Drosophila is caused by  P-elements. Which one of the following crosses between different cytotypes will lead to dysgenesis? 

In an experiment,  clones of a plant is grown in a field. The plants were observed to be plotted for frequency of plants  ( Y - axis)  against different heights ( X - axis),  a bell - shaped curve was obtained.  From the above it can be concluded that the observed variatiom in height is due to

Which one of the following viruses cause acute gastrointestinal illness due to contamination of drinking water?

The phylum in which the animals are bilaterally symmetrical in the larval stage and racially symmetrical in the adult stage is

Which of the following fungal groups has septate hyphae and reproduces asexually by budding,  conidia and fragmentation?

The most commonly used molecular tool for phylogenetic analysis involves sequencing of

The dynamics of any subpopulation within a metapopulation differs from that of a normal population in that the

Which of the following is  NOT semelparous  ?

The general relation between generation time  (T)  and  population growth rate  (r)  is described by the equation 

Which of the following is likely to contribute to the stability of an ecosystem  ?

In eusocial insects, males develop from unfertilized eggs while females develop from fertilized eggs. The ultimate consequence of this difference is that

An extraordinary sensory ability that elephants possess is

According to which evolutionary theory, there are long periods without significant evolutionary changes interrupted by short episodes of rapid evolution  ?

The mean ( u)  and  standard deviation (a) of body size in a Drosophila population are 8.5 and  2.2 mm, respectively. Under natural selection over many generations the u and  a of body size change to  8.5 and  0.8 mm,  respectively. The type of natural selection responsible for the change is called

A researcher would like to monitor changes in the level of a serum protein for which an antibody is available. Which one of the following methods would be best suited for the purpose?

Which one of the methods listed below is the most sensitive label-free quantification method for proteins

What will happen if  DNA is labelled by nick translation while doing  DNA  foot-printing?

A protein has one tryptophan and one tyrosine in its sequence.  Assume molar extinction coefficients at  280 nm of tryptophan and tyrosine as  3000 and  1500 M^-1 cm^-1, respectively. What would be the molar concentration of that protein if its absorption at  280 nm is  0.90 ?

Two groups ( Control, Treated)  are to be compared to test the effect of a treatment. Since individual variability is high in both groups, the appropriate statistical test to use is

Sting of a bee cause pain, redness and swelling. Melittin is a major peptide in bee venom. Melittin is a membrane binding peptide that is involved in activating phospholipases in the membrane. The possible target phospholipase that is activated by melittin is

The glycolysis and citric acid cycle are important pathways to generate energy in the cell. Given below are statements regarding the production of  ATP.
1. Electrons released during the oxidative steps of glycolysis and citric acid cycle produce  10 molecules of  NADH and  2 molecules of  FADH₂ per molecule of glucose.
2. Electrons released during the oxidative steps of glycolsis and citric acid cycle produce  20 molecules of  NADH and  4 molecules of  FADH ₂ per molecules of glucose.
3. The coenzymes produced are oxidized by eletron transfer chain.
4.  The conversion of ADP and P_i to  ATP  takes place in the intermembrane space of mitochondria.
  Which one of the following combinations of above statements is correct  ?

Individual  A can derive ' fitness ' benefit of  160 units by helping individual B,  but incurs a ' fitness ' cost of  50 units in doing so. Following Hamilton's Rule,  A should help B  ONLY  if  B is his :

Hydrogen bonds in proteins occur when two electronegative atoms compete for the same hydrogen atom
Donor  --  H..................  Acceptor          
The angle ' θ ' between donor and acceptor of a hydrogen bond was determined from large number of  X - ray  structures of proteins,  as  shown  below  :

Which one of the distribution of  ' 0 ' was observed from the proteins? 

Lipid rafts are involved in signal transduction in cells.  Rafts have composition different from rest of the membrane. Rafts were isolated and found to have cholesterol to sphingolipid ratio of  2 : 1 . The estimated size of the raft is 35 nm² . If the surface areas of cholesterol is  40 â„« ² and  dphingolipid is  60 â„«² , how many cholesterol and sphingolipids are present in one raft?

Glycolipids and sphingomyelin are produced by the addition of sugars or phosphorylcholine to ceramide on cytosolic and luminal surfaces respectively,  of the Golgi apparatus. Finally after such modifications, these molecules are located on the outer half of the plasma membrane.  What key events are responsible for such localization  ?

In an attempt to study the transport of secretory vasicles containing insulin along microtubules in cultured pancreatic cells, how would treatment with "colcemid " affect the transport of these vesicles? 

When circular plasmids having a centimere sequence are transformed into yeast cells.  they replicate and segregate in each cell division. However, if a linear chromosome is generated by restriction enfonuclease, the plasmids are quickly lost from the yeast. It is known that genes on the plasmids are lost because of the instability of the chromosome ends. What could be done so as to restore its stability and can be inherited?

Rec  8  is a meiosis specific cohesion that maintains centromeric cohesion between sister chromatids in meiosis I. Which of the phenotypes listed below would you predict will be manifested in a  rec8Δ  yeast? 

Eukaryotic DNA pilymerase has tightly associated primase activity but moderate  processivity.  DNA  polymerase e and  s are highly processive but lack primase activity. Given below are four statements about leading and lagging strand synthesis in eukaryotes. Which one is true  ?

Incontext to lac operon, if two bacterial strains P₁ and  P₂ with the genotypes  O^c I⁺Z^-  and O⁺1^- Z⁺ produce mero - diploid daughter strain D,  which one of the following statements correctly predicts the expression of  Z gene (𝛽 - galactosidase activity)  in all the three strains?  (O⁺,  I⁺, and  Z⁺ denote the wild type allele of the respective genes).

 In order to study the transcription factor  TFIIH,  it was cloned from a large number of human subjects.  Surprisingly, the subjects having mutation in  TFIIH,  also showed defects in their  DNA repair system. Given below are the explanations :
1.  DNA damage is always associated with transcription inhibition.
2. TFIIH  has no role in  DNA  repair.
3.  In mammalian system, TFIIH plays an active role in transcription coupled  DNA repair process.
4. Because of mutation in  TFIIH,  transcription initiation is inhibited and incompletely  synthesized  mRNAs remain attached to the template  DNA  leading to  DNA  damage.
Choose the correct answer 

The 3' end of most eukaryotic  mRNAs  is defined by the addition of a polyA tail  __ a processing reaction called polyadenylation. The addition of polyA  tail is carried out by the enzyme Poly(A) Pilymerase.  Given below are few statements about this process :
1.  Poly (A)  Polymerase is a template independent enzyme.
2. Poly (A)  Polymerase catalyses the addition of  AMP from  dATP to the  3' of  mRNA.
3. Poly(A) Polymerase is a  RNA-template dependent enzyme.
4.  Poly(A) Polymerase catalyzes the addition of  ADP from ATP to the  3' end of  mRNA.
5. Poly(A)  Polymerase catalyzes the addition of  AMP from  ATP  to the  3'  end of  mRNA.
6. Poly(A)  Polymerase catalyzes the addition of  AMP  from  dADP  to the  3'  end of  mRNA.
Choose the correct answer.

With an intention to identify the genes expressed in an organism at specific stage of development,  mRNAs  were isolated from the given organism, cDNAs were synthesized, cloned in a suitable vector and sequenced. A few of the  cDNA sequences showed no marches with the genomic  DNA sequence. Further, it was observed that these sequences were  U-rich and found to be in stretches dispersed along the sequence. The following may be possible reasons for appearance of such  RNS :
1. Splicing
2.  Alternate splicing
3.  Trans-Splicing
4.  Guide  RNA  mediated introduction of  Us involving endonuclease, terminal - U-transferase and  RNA  ligase
5.  Deaminations converting  C to  U
Which of the following is the most appropriate reasons  ?

When one isolates ribosomes from bacterial lysate,  apart from  70S,  50S and  30S  ribosomal subunits,  one also finds a small population of  100S,  130S and  150S  sub-units.  EDTA dissociates these large ribosomal subunits into  50S and  30S. suggesting that they have both the subunits. Upon addition of cations, they reassociate into  70S. But none of the other forms could be detected. What is the reason for not obtaining the  >  70S forms? 

Certain chemokines are known to suppress  HIV infection whereas proinflammatory cytokines are known to enhance infection. In order to explain these finding, control and chemokine receptor knock-out animals were treated with pro inflammatory cytokines followed by  HIV administration and then infection was assessed periodically. Which one of the graphical representation given below best explain the experimental results. 

Of the following signaling processes, whic one is  NOT involved in cellular movement or cytoskeletal changes  ?

A researcher was studying a protein ' X ' which has been observed to move across cells when an extracellular electrical stimulus is provided. An artificial peptide 'P' was prepared which resembles the structure of connexins and competitively inhibits connexon formation. Which one of the following statements will best explain the fate of protein ' X ' if the cells are treated with peptide 'P' and  then electrical stimufus is provided.

A patient with breast cancer was given a dose of radiation along with chemotherapy and was apparently cured of the tumor. After five years, a tumor was noticed in the patient 's  lungs, but the doctors confirmed that it was derived from cells of the mammary gland. The following possibilities were suggested by the doctor.
1. Bacteria infection, after radiation, led to development of the tumors in the lungs.
2. Migration of residual chemo-resistant cells from the mammary gland resulted in tumors in the lungs.
3. Epithelial -to-mesenchymal transition had occurred in the lungs.
4. Cells in the lungs were induced to become a tumor after chemotherapy and from factors secreted by mammary cells.
Which of the following is correct  ?

Chromatin condensation is driven by protein complexes called condensins which are members of a family of " structural maintenance of chromatin " (SMC)  proteins that play a key role in the organization of eukaryotic chromosomes. Condensins along with another family of  SMC proteins called cohesins  significantly contribute to chromosome segregation during mitosis. If the cells are treated with an inhibitor of cdkl phosphorylation immediately before the cells enter  M phase, which of the following statements is most likely to be true?

There are three substances A,  B and  C. Given below are the pattern of immunological responses in rabbits when (i)  A is administered along with C, (ii) B is administered along with C and (iii) A is conjugated with B and administered along with C.

Which one of the following is the correct identification?

Following are certain statements regarding seed development in plants :
A.  During final phase of development,  embryos of " orthodox " seeds become tolerant to desiccation,  dehydrate losing up to  90% of water.
B.  Dormant seeds will germinate upon rehydration while quiescent seeds require additional treatment or signals for germination
C.  Precocious germination is germination of seeds without passing through the normal quiescent and /or  dormant stage of development
D.  Abscisic acid is known to inhibit precocious germination
Which one of the following combinations is correct  ?

Development of vulva in  C. elegans is inhibited by the induction of a small number of cells by short range signals from a single inducing cell. With reference to this,  following statements were put forward.
1.  When the anchor cell was ablated early in development, no vulva formed.
2. In a dominant negative mutant of let-23 , a primary vulva formed but the secondary vulva formation did not take place.
3. A cell adopting a primary fate inhibits adjacent cells from adopting the same fate by lateral inhibition involving  LIN - 39 and  also induces the secondary fate in these cells.
4.  A constitutive signal from the hypodermis inhibits the development of both the primary and secondary fates but it is overruled by the initial signal from the anchor cell.
Which of the above statements is true?

Which one of the following about development of sea urchin embryos is TRUE  ?

What will happen if wingless  RNAi is expressed in wingless expressing cells from the stage when this gene initiates its expression in a developing Drosophila embryo?
1. The enhanced expression of wingless thus caused will broaden the area of engrailed expression.
2. Since wingless protein makes a long range gradient, its effect will not be seen in the same segment.
3. The posterior compartment of each future segment will get affected.
4. Since engrailed expression is initiated by pair rule genes, the posterior segment will not be affected.
Which one of the following will most appropriately answer the question?

Column  A                            Column B                                                       Column C
(i)  Invagination (i)  Movement of epithelial cells as a unit to         (i)  Hypoblast in birds
                                     enclose deeper layers of the embryo
(ii) Involution          (ii) Splitting of one cellular sheet into two          (ii)  Ectoderm in amphibians
(iii) Ingression       (iii)  Infolding of epithelium                                   (iii)  Mesoderm in amphibians
(iv) Delamination    (iv) Migration of individual cells from               (iv)  Endoderm in sea urchin
                                        surface into interior of the embryo
(v) Epiboly               (v) Inward movement of expanding outer layer    (v)  Mesoderm in sea urchin
                                       so that it spreads over the internal surface
                                     of remaining external cells
Which one of the following is the correct combination? 

Formation of digits and sculpting the tetrapod limb requires death of specific cells in the limb in a programmed manner. Which one of the following interactions could explain proper limb formation?

Light is an important factor for plant growth and development. There are several photoreceptors in higher plants such as Arabidopsis thaliana involved in perception of various wavelengths of light. Some statements are given below related to photoreceptors :
A.  Red light photoreceptors are represented by a gene family.
B.  Phytochrome  C is the most prominent photoreceptor to perceive red light.
C. Cryptochrome 1 and  cryptochrome  2 have evolved from bacterial  DNA  photolyases.
D.  Far-red light  is  perceived by phytochrome  D.
Which one of the following combinations of above statements is correct?

Pyruvate dehydrogenase is subject to feed back inhibition by its products in glycolysis. Some of the chemical compounds which might be involved in the process, are listed below  :
1.  NADH                     2. FAD
3.  Acetyl-CoA             4.  Acetaldehyde
Which one of the following combinations of above chemical compounds is involved in feedback inhibition of pyruvate dehydro-genase?

Carbohydrates synthesized by photo-synthesis are concerned into sucrose and transported via phloem to other parts of the plant. The following aspects are associated with sucrose uploading in phloem and its transport:
1. Both reducing and non-reducing sugars are transported efficiently through phloem.
2. Sucrose uploading can be both symplastic and apoplastic.
3. The route of phloem uploading is-mesophyll cells ----> phloem parenchyma ---> companion cells  ---> sieve tubes.
4. Transport in sieve tubes is as per the 'pressure -flow model'.
Which one of the following combinations is correct?