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Objective Questions

Latest MH SET Life Science Exam Question (Objective Questions), MCQ in English

Subjects : Life Science

Question Bank MH SET Life Science Exam - English
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Life Science

Question 1Single Answer
AB is the diameter of a circle. The chord CD is perpendicular to AB intersecting it at P. If CP = 2 and PB = 1, the radius of the circle is :

  1. A
    1
  2. B
    2.5
  3. C
    2
  4. D
    5
Question 2Single Answer
A shopkeeper purchases a product for Rs.100 and sells it making a profit of 10 %. The customer resells it to the same shopkeeper incurring a loss of 10 %. In these dealings the shopkeeper makes :
  1. A
    No profit, no loss
  2. B
    Rs. 11
  3. C
    Rs. 1
  4. D
    Rs. 20
Question 3Single Answer
The product of the perimeter of a triangle, the radius of its in-circle, and a number gives the area of the triangle. The number is :
  1. A
    1/4
  2. B
    1/3
  3. C
    1/2
  4. D
    1
Question 4Single Answer
Starting from a point A you fly one mile south, then one mile east, then one mile north which brings you back to point A. Which of the following MUST be true ?
  1. A
    You are at the North pole
  2. B
    You are in the Eastern hemisphere
  3. C
    You are in the Western hemisphere
  4. D
    You are at the South pole
Question 5Single Answer
Three boxes are coloured red, blue and green and so are three balls. In how many ways can one put the balls one in each box such that no ball goes into the box of its own colour ?
  1. A
    1
  2. B
    2
  3. C
    3
  4. D
    4
Question 6Single Answer
There are two buckets A and B. Initially A has 2 litres of water and B is empty. At every hour 1 litre of water is transferred from A to B followed by returning 1/2 litre back to A from B half an hour later. The earliest A will get empty in :
  1. A
    5 hours
  2. B
    4 hours
  3. C
    3 hours
  4. D
    2 hours
Question 7Single Answer
Density of a rice grain is 1.5g/cc and bulk density of rice heap is 0.80 g/cc. If a 1 litre container is completely filled with rice, what will be the approximate volume of pore space in the container ?
  1. A
    350 cc
  2. B
    465 cc
  3. C
    550 cc
  4. D
    665 cc
Question 8Single Answer
What is the minimum number of moves required to transform figure 1 to figure 2 ? A move is defined as removing a coin and placing it such that it touches two other coins in its new position .

  1. A
    1
  2. B
    2
  3. C
    3
  4. D
    4
Question 9Single Answer
It takes 5 days for a steamboat to travel from A to B along a river. It takes 7 days to return from B to A. How many days will it take for a raft to drift from A to B (assuming all speed are constant) ?
  1. A
    13
  2. B
    35
  3. C
    6
  4. D
    12
Question 10Single Answer
How many times starting at 1: 00 pm would the minute and hour hands of a clock make an angle of 40ยฐ with each other in the next 6 hours ?
  1. A
    6
  2. B
    7
  3. C
    11
  4. D
    1
Question 11Single Answer
The graph shows cumulative frequency, percentage of research scholars and the number of papers published by them. Which of the following statements is true ?

  1. A
    Majority of the scholar published more than 4 papers
  2. B
    60 % of the scholar published at least 2 papers
  3. C
    80 % of the scholar published at least 6 papers
  4. D
    30 % of the scholars have not published any paper
Question 12Single Answer
The random errors associated with the measurement of P and Q are 10 % and 2%. respectively. What is the maximum percentage random error in P/Q ?
  1. A
    12.0
  2. B
    9.8
  3. C
    8.0
  4. D
    10.2
Question 13Single Answer
If a person travels x % faster than normal, he reaches y minutes earlier than normal. What is his normal time of travel ?
  1. A
  2. B
  3. C
  4. D
Question 14Single Answer
Pre - Ph.D exam score of 10 students are plotted against their M.Sc. marks. Which of the following is true ?

  1. A
    Two students have scored better in Pre - Ph.D than their M.Sc. exam
  2. B
    (b) All those students who scored 50 in Pre - Ph.D scored more marks in their M.Sc. exam
  3. C
    Two students scored the same marks in their Pre - Ph.D and M.Sc. exams
  4. D
    The student who scored maximum in M.Sc. is the only student to get maximum in Pre - Ph.D exam
Question 15Single Answer
What is the average value of y for the range of x shown in the following plot ?

  1. A
    Zero
  2. B
    1
  3. C
    1.5
  4. D
    2
Question 16Single Answer
A fair die was thrown three times and the outcome was repeatedly six. If the die is thrown again what is the probability of getting six ?
  1. A
    1/6
  2. B
    1/216
  3. C
    1/1296
  4. D
    1
Question 17Single Answer
What is the volume of soil in an open pit of size 2 m ร— 2 m ร— 10 cm ?
  1. A
    40 m3
  2. B
    0.4 m3
  3. C
    0 m3
  4. D
    4.0 m3
Question 18Single Answer
If a plant with green leaves is kept in a dark room with only green light on, which one of the following would we observe ?
  1. A
    The plant appears brighter than the surroundings
  2. B
    The plant appears darker than the surroundings
  3. C
    We cannot distinguish the plant from the surroundings
  4. D
    It will have above normal photosynthetic activity
Question 19Single Answer
The distance from city P to city Q is 27 km. A and B start walking from P towards Q at speeds of 5 km/hr and 7 km/hr, respectively. B reaches Q, returns immediately, and meets A at R. What is the distance between Pand R ? (assume all three cities to be in one straight line)
  1. A
    12.5 km
  2. B
    22.5 km
  3. C
    4.5 km
  4. D
    13.5 km
Question 20Single Answer
A floor of size 13 x 24 is to be paved using square tiles only. What is the smallest number of tiles needed to do this ?
  1. A
    6
  2. B
    15
  3. C
    8
  4. D
    9
Question 21Single Answer
Following statements are made about uncompetitive inhibition of an enzyme :
(a) Uncompetitive inhibitor binds to both free enzyme as well as an enzyme - substrate complex.
(b) Addition of uncompetitive inhibitor lowers the Vmax of the reaction.
(c) Apparent KM of the enzyme is lowered.
(d) Apparent KM of the enzyme remains unchanged.
Which one of the following option represents the correct combination of the statments ?
  1. A
    (b) and (c)
  2. B
    (a) and (c)
  3. C
    (a) and (b)
  4. D
    (a) and (d)
Question 22Single Answer
Following are the pKa's of the ionizable groups in lysine :
pKa1 = 2.16 (α โ€“ carboxylic group)
pKa2 = 9.06(α โ€“ amino group)
pKa3 = 10.54(εย โ€“ amino group)
Which one of the following options represents the pl of lysine ?
  1. A
    7.25
  2. B
    5.61
  3. C
    6.35
  4. D
    9.8
Question 23Single Answer
The enzyme alkaline phosphatase was tested for its catalytic activity using the substrate para-nitrophenylphosphate. The KM obtained was 10 mM and Vmax was 100 ยต mol/min. Which one of the following options represents the initial velocity of the reaction at a substrate concentration of 10 mM?
  1. A
    50 ยต mol/min
  2. B
    100 ยต mol/min
  3. C
    500 ยต mol/min
  4. D
    20 ยต mol/min
Question 24Single Answer
How many hydrogen bonds involving the backbone CO and NH can be observed in an α - helix consisting, of 15 amino acid residues ?
  1. A
    10
  2. B
    11
  3. C
    12
  4. D
    13
Question 25Single Answer
Progression across Gl/S boundary followed by entry into S-phase is promoted by the activation of which one of the following protein complexes?
  1. A
    Cdk4/Cyclin D
  2. B
    Cdk2/ Cyclin E
  3. C
    Cdk4, 6/Cyclin
  4. D
    Cdk4, 6/Cyclin D.,E
Question 26Single Answer
In eukaryotic cells, covalently attached lipids help to anchor some water soluble proteins to the plasma membrane. One group of cytosolic proteins are anchored to the cytosolic face of membrane by a fatty acyl group (e.g. myristate or palmitate). These groups are generally covalently attached to which amino acids present at the N-terminus of the polypeptide chain ?
  1. A
    Glycine
  2. B
    Tyrosine
  3. C
    Serine
  4. D
    Lysine
Question 27Single Answer
The movement of proteins bigger than 50 kDa across the nuclear envelope requires :
  1. A
    Sec 61
  2. B
    Tom 20
  3. C
    Importin β
  4. D
    Tim 44
Question 28Single Answer
Iron - sulphur clusters [Fe - S] are the key prosthetic groups that carry electrons in all of the below EXCEPT :
  1. A
    NADH โ€“ CoQ reductase
  2. B
    Succinate โ€“ CoQ reductase
  3. C
    Cytochrome C oxidase
  4. D
    CoQH2 โ€“ Cytochrome C reductase
Question 29Single Answer
In bacteria many of the tRNA genes do not contain the CCA sequence found at the 3' end of tRNA. In this context which one of the following statements represents the correct explanation ?
  1. A
    In these tRNAs amino acylation occurs at the 3' end of the tRNA irrespective of the presence of the - CCA sequence
  2. B
    CCA sequence is added to these tRNA transcripts in a DNA template independent manner
  3. C
    These tRNAs exploit the process of transsplicing to include a CCA sequence at their 3' end
  4. D
    The absence of CCA sequence occurred only in the last common ancestor (LCA) during the course of evolution and the current day tRNA genes always possess a sequence to encode the CCA end of the tRNA
Question 30Single Answer
Some cells possess peptides which contain D-form of amino acids. How do they arise ?
  1. A
    These peptides are produced by ribosomes by incorporating D - amino acids at specific positions
  2. B
    Ribosome makes peptides with L - amino acids only. However, some of the amino acids in the peptides are replaced by D - amino acids by a pathway that involves excision of the L - amino acids
  3. C
    The peptides with the D - amino acids are produced in a ribosome - independent manner
  4. D
    Peptides with D-amino acids exist only in archeae where they are made by the presence of racemases
Question 31Single Answer
All of the following statements about bacterial transcription termination are true EXCEPT :
  1. A
    some - terminator sequences require Rho protein for termination
  2. B
    inverted repeat and 'T' rich non - template strand define intrinsic terminators
  3. C
    Rho - dependent terminators may possess inverted repeat elements
  4. D
    Nus A is necessary for intrinsic transcription termination
Question 32Single Answer
Which one of the following proteins is essential for both the initiation of DNA replication as well as the continued advance of the replication fork ?
  1. A
    ORC
  2. B
    Geminin
  3. C
    CDc45
  4. D
    Cdc6
Question 33Single Answer
Which one of the following combinations represents the major protein or protein complex involved in chromatin condensation in yeast and human, respectively ?
  1. A
    HP1 and SIR Complex
  2. B
    SIR complex and HP1
  3. C
    HP1 and Su(var)
  4. D
    SIR complex and Su(var)
Question 34Single Answer
Which of the following is the causative agent of filariasis ?
  1. A
    Listeria monocytogenes
  2. B
    Cryptococcus neoformans
  3. C
    Francisella tularensis
  4. D
    Brugiya malayi
Question 35Single Answer
The cytoplasmic domain of the receptor of which of the following proteins does NOT function as tyrosine kinase ?
  1. A
    Epidermal growth factor
  2. B
    Platelet derived growth factor
  3. C
    Insulin
  4. D
    Asialoglycoprotein
Question 36Single Answer
Tumors are generally classified by :
  1. A
    the virus which caused them
  2. B
    the person who discovered them
  3. C
    their metastatic ability
  4. D
    the tissue or cell of origin
Question 37Single Answer
A breakthrough in cancer therapy is expected where T - cells are taken from a patient are modified in the laboratory to attack cancer cells before re - infusion in the patient. These T - cells are called:
  1. A
    cancer associated receptor T - cells
  2. B
    chimeric antigen - receptor T - cells
  3. C
    chimeric B and T cell
  4. D
    cancer antigens recognition T - cells
Question 38Single Answer
Which one of the following statements with respect to development in amphibians is correct ?
  1. A
    Gastrulation begins with the invagination of bottle cells, followed by coordinated involution of the mesodermal precursors and the epiboly of the prospective ectoderm
  2. B
    The organizer induces the Nieuwkoop centre
  3. C
    The organizer is formed by the accumulation of b - catenin
  4. D
    In the absence of BMP inhibitors ectodermal cells form neural tube
Question 39Single Answer
During normal development of sea urchin, b - catenin accumulates predominantly in the micromeres, which are fated to become endoderm and mesoderm. If GSK - 3 is blocked in the developing embryo:
  1. A
    b - catenin accumulation in the nuclei of large micromeres will be inhibited leading to formation of ectodermal ball
  2. B
    b - catenin will accumulate in the nuclei of all blastula cells leading to an ectodermal ball
  3. C
    b - catenin will accumulate in the nuclei of all blastula cells leading to animal cells getting specified as endoderm and mesoderm
  4. D
    b - catenin which accumulate in the nuclei of large micromeres will be inhibited leading to animal cells getting specified as endoderm and mesoderm
Question 40Single Answer
In which of the following stages of Arabidopsis embryogenesis do the visible distinctions between the adaxial and abaxial tissues of the cotyledons become initially apparent ?
  1. A
    Globular stage
  2. B
    Zygotic stage
  3. C
    Torpedo stage
  4. D
    Mature stage
Question 41Single Answer
In a transplantation experiment, the area of presumptive ectoderm from an early frog gastrula was transplanted to a region of the newt gastrula destined to become parts of the mouth. The resulting salamander larvae had frog like mouth parts (frog tadpole suckers) instead of balancers as observed during development of wild type newt embryo. This is an example of :
  1. A
    Determination
  2. B
    Genetic specificity of interaction
  3. C
    Regional specificity of interaction
  4. D
    Autonomous specification
Question 42Single Answer
Which of the following ' R ' gene products do not contain NBS - LRR domain ?
  1. A
    RPS2 protein of Arabidopsis
  2. B
    Xal protein of rice
  3. C
    N protein of tobacco
  4. D
    Mlo protein of barley
Question 43Single Answer
Photochemically generated ATP is consumed in which one of the following phases of Calvin- Benson cycle ?
  1. A
    Only carboxylation
  2. B
    Only regeneration
  3. C
    Carboxylation and reduction
  4. D
    Reduction and regeneration
Question 44Single Answer
Dirigent proteins predominantly play an important role in biosynthesis of :
  1. A
    lignans
  2. B
    alkaloids
  3. C
    terpenoids
  4. D
    amino acids
Question 45Single Answer
Which one of the following is used in organification of tyrosine residues in thyroglobulin protein, during thyroid hormone biosynthesis ?
  1. A
    Iodine
  2. B
    Reduced iodine
  3. C
    Oxidized iodine
  4. D
    Hydrogen iodide
Question 46Single Answer
The dark current in retina is due to :
  1. A
    Closing of Na+ channels in the outer segment of photoreceptors
  2. B
    Opening of K+ channels in the inner segment of photoreceptors
  3. C
    Opening of Na+ channels in the outer segment of photoreceptors
  4. D
    Closing of K+ channels in the outer segment of photoreceptors
Question 47Single Answer
Which one of the following is not present in the filtration slit diaphragm ?
  1. A
    NEPH1
  2. B
    Paxillin
  3. C
    Nephrin
  4. D
    NEPH2
Question 48Single Answer
DNA was isolated from a strain in bacterium with genotype a+ b+ c+ d+ e+ and transformed into a bacterial strain aโ€“ bโ€“ cโ€“, dโ€“ eโ€“. The transformants were tested for the presence of the donated genes.
The cotransformed genes were found as follows: a+ and b+ ; c+ and e+ ; d+ and c+ ; b+ and d+; What is the order of genes on the bacterial chromosome ?
  1. A
    a b c d e
  2. B
    a c b e d
  3. C
    a b c e d
  4. D
    a b d c e
Question 49Single Answer
A fly with apricot coloured eye was crossed with a sepia eyed fly of opposite sex. In F1 all flies were wild type. The genes responsible for the two phenotypes were :
  1. A
    allelic
  2. B
    non - allelic
  3. C
    pseudo - allelic
  4. D
    paralogous genes
Question 50Single Answer
Human polydactyly traits having extra fingers or toes are caused by a dominant allele. In a screening it was found that out of 42 individuals having an allele for polydactyly, only 38 of them were polydactylus. Which of the following is the correct interpretation of the observation ?
  1. A
    The penetrance of polydactyly is estimated to be 90%
  2. B
    The expressivity of polydactyly is 90%
  3. C
    This is an example of variable expressivity
  4. D
    The polydactyly trait is showing complete penetrance
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