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Latest MHSRB Telangana Pharmacist Exam Question (Objective Questions), MCQ in English

Subjects : Pharmacy

Question Bank MHSRB Telanagana Pharmacist Exam - English
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Pharmacy

Question 1Single Answer
Creaming is a ________ process.
  1. A
    Reversible
  2. B
    Irreversible
  3. C
    Downward
  4. D
    Both (a) and (c)
Question 2Single Answer
o/w emulsions normally cream in _______ direction.
  1. A
    Downward
  2. B
    Upward
  3. C
    First up and then down
  4. D
    First down then up
Question 3Single Answer
 ______ is an example of non-ionic polymer.
  1. A
    Cellulose
  2. B
    Pectin
  3. C
    Glucose
  4. D
    Methyl cellulose
Question 4Single Answer
Electrolytes are added in suspensions to _____ the zeta potential.
  1. A
    Neutralize
  2. B
    Decrease
  3. C
    Increase
  4. D
    Stabilize
Question 5Single Answer
The sedimentation volume of an ideal suspension should be _____
 
  1. A
    One
  2. B
    Greater than one
  3. C
    Zero
  4. D
    Less than one
Question 6Single Answer
Which combination correctly describes a flocculated pharmaceutical suspension?
  1. A
    Particles form loose aggregates and the supernatant becomes clear
  2. B
    Particles form a compact hard cake and the supernatant remains turbid
  3. C
    Sedimentation is negligible and particles remain completely dispersed
  4. D
    Redispersion becomes progressively impossible
Question 7Single Answer
Which law is commonly used to describe the sedimentation velocity of spherical particles in a dilute pharmaceutical suspension?
  1. A
    Stokes' law
  2. B
    Henry's law
  3. C
    Raoult's law
  4. D
    Beer-Lambert law
Question 8Single Answer
According to the phase-volume concept, approximately what maximum volume fraction of monodisperse spherical droplets corresponds to close packing before severe instability becomes likely?
  1. A
    0.26
  2. B
    0.50
  3. C
    0.74
  4. D
    0.90
Question 9Single Answer
Which among the following is the chief ingredient of anti-diarrhoeal mixture?
  1. A
    Charcoal
  2. B
    Kaolin
  3. C
    Calamine
  4. D
    Aluminum Hydroxide
Question 10Single Answer
Which rheological test applies a constant stress and measures time-dependent deformation of a semisolid material?
  1. A
    Creep test
  2. B
    Pycnometry
  3. C
    Nephelometry
  4. D
    Refractometry
Question 11Single Answer
Compared with its continuous aqueous phase, the apparent viscosity of an oil-in-water emulsion is generally?
  1. A
    Higher
  2. B
    Always lower
  3. C
    Exactly identical
  4. D
    Always zero
Question 12Single Answer
According to Stoke's equation, the creaming of emulsion will take place in _____ direction, if the density of the dispersed phase is more than that of the dispersion medium.
 
 
  1. A
    Downward
  2. B
    Upward
  3. C
    Centre
  4. D
    Both (a) and (b)
Question 13Single Answer
____ of an emulsion occurs when the distributions  is of globules is not uniform.
  1. A
    Caking
  2. B
    Breaking
  3. C
    Creaming
  4. D
    Coalescence
Question 14Single Answer
The commercial method for the preparation of emulsions is ______
 
  1. A
    Homogenization
  2. B
    Lyophilization
  3. C
    Centrifugation
  4. D
    Both (a) and (c)
Question 15Single Answer
According to Stokes' law, which change most directly reduces the rate of creaming in an emulsion?
  1. A
    Decreasing globule size
  2. B
    Increasing globule size
  3. C
    Decreasing continuous-phase viscosity
  4. D
    Increasing the density difference between phases
Question 16Single Answer
The ratio of oil : water : gum, used for the preparation of a primary emulsion containing a fixed oil is ____
  1. A
    4 : 4 : 2
  2. B
    4 : 2 : 1
  3. C
    1 : 2 : 4
  4. D
    2 : 4 : 4
Question 17Single Answer
The percentage of sucrose in simple syrup I.P is ___
  1. A
    66.7% w/w
  2. B
    85% w/w
  3. C
    56% w/w
  4. D
    33% w/w
Question 18Single Answer
Commonly used solvent in throat paint is ____
  1. A
    Castor Oil
  2. B
    Sucrose Syrup
  3. C
    Glycerin
  4. D
    Alcohol
Question 19Single Answer
Lugol's solution is an aqueous solution containing iodine together with which substance to enhance iodine solubility?
  1. A
    Potassium iodide
  2. B
    Sodium bicarbonate
  3. C
    Calcium chloride
  4. D
    Magnesium sulfate
Question 20Single Answer
Which of the following processes is used for the extraction of volatile oils from plants?
  1. A
    Simple Distillation
  2. B
    Steam Distillation
  3. C
    Extraction
  4. D
    Soxhlation
Question 21Single Answer
In atherosclerosis, the serum level of____decreases.
  1. A
    Triglycerides
  2. B
    VLDL
  3. C
    HDL
  4. D
    LDL
Question 22Single Answer
Which drug can significantly increase plasma digoxin concentrations and thereby increase the risk of digitalis toxicity?
  1. A
    Quinidine
  2. B
    Potassium chloride
  3. C
    Lidocaine
  4. D
    Magnesium sulfate
Question 23Single Answer
When quinidine is initiated in a patient receiving digoxin, which measure is particularly important?
  1. A
    Monitor digoxin concentration and adjust its dose when necessary
  2. B
    Routinely double the digoxin dose
  3. C
    Discontinue all potassium intake
  4. D
    Administer digoxin only intramuscularly
Question 24Single Answer
Name a substitute of enalapril.
  1. A
    Losartan
  2. B
    Rosiglitazone
  3. C
    Omeprazole
  4. D
    Famotidine
Question 25Single Answer
Antihypertensive drugs                                 Mode of action
1. Methyldopa                                               (A) Ganglion blocker
2. Hydralazine                                              (B) Depletion of catecholamines
3. Reserpine                                                 (C) Direct action on arterioles
4. Mecamylamine                                         (D) False neurotransmitter
  1. A
    1-D, 2-C, 3-B, 4-A
  2. B
    1-A, 2-C, 3-D, 4-B
  3. C
    1-B, 2-A, 3-D, 4-C
  4. D
    1-A, 2-B, 3-C, 4-D
Question 26Single Answer
Match the cardiovascular drug with its principal pharmacological action:
1. Papaverine – Vasodilator
2. Verapamil – Calcium-channel blocker
3. Hydralazine – Direct arteriolar vasodilator
4. Dobutamine – β₁-adrenergic agonist
Which matching sequence is correct?
  1. A
    1, 2, 3 and 4 are correctly matched
  2. B
    Only 1 and 2 are correctly matched
  3. C
    Only 2 and 3 are correctly matched
  4. D
    Only 3 and 4 are correctly matched
Question 27Single Answer
Which of the following are the potential targets for designing antihypertensive drugs?
(A) H2-receptors
(B) Proton pump
(C)  - adrenergic receptors
(D) Calcium channel proteins
  1. A
    A and B
  2. B
    C and D
  3. C
    B and D
  4. D
    A and D
Question 28Single Answer
Hypotensive agents                                Mode of action
1. Clonidine                                      (A) Direct action on blood vessels
2. Captopril                                        (B) - adrenoceptor antagonist
3. Prazosin                                        (C) Decreases sympathetic activity through brain
4. Minoxidil                                        (D) Angiotensin converting enzyme inhibitor
  1. A
    1-A, 2-B, 3-C, 4-D
  2. B
    1-D, 2-C, 3-A, 4-B
  3. C
    1-C, 2-B, 3-D, 4-A
  4. D
    1-C 2-D, 3-B, 4-A
Question 29Single Answer
Which statement about digoxin is correct?
  1. A
    Its elimination half-life in adults with normal renal function is approximately 36–48 hours
  2. B
    It is metabolized almost completely by the liver
  3. C
    It primarily accelerates AV nodal conduction
  4. D
    Its principal elimination pathway is pulmonary excretion
Question 30Single Answer
Digitalis glycosides are used in congestive heart failure as they increase the____.
  1. A
    Force of myocardial contraction
  2. B
    Cardiac filling pressure
  3. C
    Heart rate
  4. D
    Venous pressure
Question 31Single Answer
Digitalis is used in congestive heart failure. It acts by ____.
  1. A
    Decreasing the intracellular sodium levels
  2. B
    Activating adenylyl cyclase to produce cAMP
  3. C
    Decreasing the release of calcium from sarcoplasmic reticulum
  4. D
    Inhibiting the action of Na+ -K+ -ATPase enzyme
Question 32Single Answer
Concomitant administration of ____ increases the risk of digitalis toxicity.
  1. A
    Lidocaine
  2. B
    Triamterene
  3. C
    Hydrochlorothiazide
  4. D
    Captopril
Question 33Single Answer
___is a cardioselective -blocker with vasodilatory action.
  1. A
    Atenolol
  2. B
    Bisoprolol
  3. C
    Nebivolol
  4. D
    Pindolol
Question 34Single Answer
___is specifically indicated for the treatment of supraventricular tachyarrhythmias.
  1. A
    Mexiletine
  2. B
    Diltiazem
  3. C
    Propranolol
  4. D
    Nifedipine
Question 35Single Answer
Which angiotensin-II receptor blocker is used in hypertension?
  1. A
    Valsartan
  2. B
    Amlodipine
  3. C
    Atenolol
  4. D
    Enalapril
Question 36Single Answer
Why may metoprolol be preferred over propranolol when β₁-selectivity is clinically desirable?
  1. A
    Metoprolol is relatively selective for β₁-adrenoceptors
  2. B
    Metoprolol is an irreversible α-blocker
  3. C
    Metoprolol is a calcium-channel blocker
  4. D
    Metoprolol stimulates β₂-adrenoceptors
Question 37Single Answer
Which cardiac drug exerts its positive inotropic action primarily by stimulating β₁-adrenoceptors and increasing intracellular cAMP?
  1. A
    Dobutamine
  2. B
    Digitoxin
  3. C
    Nicardipine
  4. D
    Sotalol
Question 38Single Answer
Which antianginal drug may produce reflex tachycardia because of marked vasodilation?
  1. A
    Nitroglycerin
  2. B
    Timolol
  3. C
    Atenolol
  4. D
    Ivabradine
Question 39Single Answer
Which drug is particularly useful in vasospastic or Prinzmetal angina because it blocks L-type calcium channels and relaxes coronary vascular smooth muscle?
  1. A
    Nifedipine
  2. B
    Timolol
  3. C
    Digoxin
  4. D
    Hydrochlorothiazide
Question 40Single Answer
Sublingual nitroglycerine tablet has a duration of action of___.
  1. A
    3-5 mins
  2. B
    10-30 mins
  3. C
    1-2 hours
  4. D
    8-10 hours
Question 41Single Answer
Which antihypertensive drug inhibits the renin angiotensin-aldosterone system?
  1. A
    Propranolol
  2. B
    Methyldopa
  3. C
    Reserpine
  4. D
    Enalapril
Question 42Single Answer
Terazosin lowers blood pressure primarily by blocking which receptors?
  1. A
    α₁-adrenoceptors
  2. B
    β₁-adrenoceptors
  3. C
    β₂-adrenoceptors
  4. D
    H₂-receptors
Question 43Single Answer
Clonidine lowers blood pressure predominantly by stimulating which central receptors?
  1. A
    α₂-adrenoceptors
  2. B
    β₁-adrenoceptors
  3. C
    H₂-receptors
  4. D
    D₂-receptors
Question 44Single Answer
Which condition is an important contraindication to the use of a nonselective β-blocker such as propranolol?
  1. A
    Bronchial asthma with bronchospasm
  2. B
    Essential hypertension
  3. C
    Migraine prophylaxis
  4. D
    Stable angina pectoris
Question 45Single Answer
Which one of the following sentence is true for nitrates?
  1. A
    They have diuretic effect
  2. B
    They are drugs of choice in hypertension
  3. C
    Glyceryl trinitrates is used in the rapid relief from angina
  4. D
    Tolerance is developed only to adverse effects but not to antianginal effect.
Question 46Single Answer
Furosemide is an example of____.
  1. A
    Potassium-sparing diuretic
  2. B
    Carbonic anhydrase inhibitor
  3. C
    Thiazide diuretic
  4. D
    Loop diuretic
Question 47Single Answer
Which of the following is a calcium channel blocker?
  1. A
    Clonidine
  2. B
    Losartan
  3. C
    Acebutalol
  4. D
    Amlodipine
Question 48Single Answer
Which direct-acting arteriolar vasodilator relaxes vascular smooth muscle and is used in the treatment of hypertension?
  1. A
    Hydralazine
  2. B
    Physostigmine
  3. C
    Pilocarpine
  4. D
    Pralidoxime
Question 49Single Answer
Thiazide diuretics do not cause which of the following adverse effect?
  1. A
    Hypokalaemia
  2. B
    Hyperuricaemia
  3. C
    Hypoglycaemia
  4. D
    Hypercalcaemia
Question 50Single Answer
____ is the most commonly used diuretic along with antihypertensive drugs.
  1. A
    Acetazolamide
  2. B
    Mannitol
  3. C
    Spironolactone
  4. D
    Hydrochlorothiazide
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