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Question for OPSC Assistant Professor Biochemistry - Quiz / Questions / MCQ in English

Last Update on : October 10, 2026

Duration: 180 · Questions: 200 · Max Marks: 200

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Latest OPSC Assistant Professor Biochemistry Exam Question (Objective Questions), MCQ in English

Subjects : Concerned Subject (Biochemistry)

Question Bank OPSC Assistant Professor (Biochemistry) Exam - English

Concerned Subject (Biochemistry)

Q 1 :
Which structural feature is uniquely associated with eukaryotic chromatin organization?
  1. A.Presence of operons
  2. B.Absence of introns
  3. C.Single origin of replication
  4. D.Association of DNA with histone octamers
Q 2 :
The cytoskeletal element that resists tensile stress and maintains cell integrity is?
  1. A.Intermediate filaments
  2. B.Actin filaments
  3. C.Microtubules
  4. D.Myosin fibers
Q 3 :
Which organelle is the primary site of phospholipid and steroid synthesis?
  1. A.Rough endoplasmic reticulum
  2. B.Golgi apparatus
  3. C.Smooth endoplasmic reticulum
  4. D.Lysosome
Q 4 :
Dynein differs from kinesin mainly in its directionality of movement toward the?
  1. A.Plus end of microtubule
  2. B.Actin filament end
  3. C.Minus end of microtubule
  4. D.Centrosome independent pathway
Q 5 :
Cardiolipin is predominantly localized in which membrane?
  1. A.Outer mitochondrial membrane
  2. B.Endoplasmic reticulum membrane
  3. C.Plasma membrane
  4. D.Inner mitochondrial membrane
Q 6 :
Which junction provides mechanical strength by anchoring intermediate filaments between adjacent cells?
  1. A.Desmosome
  2. B.Gap junction
  3. C.Tight junction
  4. D.Adherens junction
Q 7 :
Integrins primarily mediate which type of cellular interaction?
  1. A.Cell–matrix adhesion
  2. B.Cell–cell adhesion
  3. C.Tight junction sealing
  4. D.Ion channel formation
Q 8 :
Which extracellular matrix component provides tensile strength to tissues?
  1. A.Elastin
  2. B.Collagen
  3. C.Proteoglycans
  4. D.Fibronectin
Q 9 :
The G1 checkpoint of the cell cycle primarily ensures?
  1. A.Adequate cell size and DNA integrity
  2. B.Proper spindle formation
  3. C.Completion of DNA replication
  4. D.Cytokinesis
Q 10 :
Which cyclin–CDK complex is critical for the G1 to S phase transition?
  1. A.Cyclin E–CDK2
  2. B.Cyclin D–CDK4
  3. C.Cyclin A–CDK2
  4. D.Cyclin B–CDK1
Q 11 :
The spindle assembly checkpoint monitors the?
  1. A.Chromosome alignment at metaphase plate
  2. B.DNA damage
  3. C.Completion of cytokinesis
  4. D.Initiation of transcription
Q 12 :
Which tissue type is specialized for rapid electrical signal transmission?
  1. A.Connective tissue
  2. B.Nervous tissue
  3. C.Epithelial tissue
  4. D.Muscle tissue
Q 13 :
Actin polymerization is directly regulated by which nucleotide?
  1. A.UTP
  2. B.GTP
  3. C.CTP
  4. D.ATP
Q 14 :
The Golgi apparatus modifies proteins mainly by?
  1. A.Proteolysis
  2. B.Glycosylation and sulfation
  3. C.Phosphorylation
  4. D.Deamination
Q 15 :
Which protein links actin filaments to transmembrane proteins in adherens junctions?
  1. A.Cadherin
  2. B.Integrin
  3. C.Catenin
  4. D.Claudin
Q 16 :
Which organelle lacks its own DNA?
  1. A.Mitochondria
  2. B.Peroxisome
  3. C.Chloroplast
  4. D.Nucleus
Q 17 :
Which cytoskeletal component is absent in plant cells?
  1. A.Actin
  2. B.Microtubules
  3. C.Intermediate filaments
  4. D.Cellulose fibers
Q 18 :
The observable expression of a gene is termed as?
  1. A.Genotype
  2. B.Phenotype
  3. C.Allele
  4. D.Locus
Q 19 :
An organism possessing two identical alleles for a gene is described as?
  1. A.Hybrid
  2. B.Heterozygous
  3. C.Homozygous
  4. D.Hemizygous
Q 20 :
Mendel’s law of segregation is best explained by separation of alleles during?
  1. A.Fertilization
  2. B.Meiosis II
  3. C.Meiosis I
  4. D.Mitosis
Q 21 :
A test cross is performed to determine the?
  1. A.Genotype of a dominant individual
  2. B.Phenotype
  3. C.Allelic frequency
  4. D.Mutation rate
Q 22 :
In incomplete dominance, the heterozygote exhibits?
  1. A.Dominant phenotype
  2. B.Recessive phenotype
  3. C.Lethal phenotype
  4. D.Intermediate phenotype
Q 23 :
The ABO blood group system is an example of?
  1. A.Codominance and multiple alleles
  2. B.Epistasis
  3. C.Polygenic inheritance
  4. D.Pleiotropy
Q 24 :
Polytene chromosomes are characteristically found in?
  1. A.Salivary glands of Diptera
  2. B.Germ cells
  3. C.Liver cells
  4. D.Neurons
Q 25 :
Lampbrush chromosomes are typically observed during?
  1. A.Spermatogenesis
  2. B.Mitosis
  3. C.Oogenesis
  4. D.Fertilization
Q 26 :
A Robertsonian translocation involves?
  1. A.Fusion of two acrocentric chromosomes
  2. B.Exchange between homologous chromosomes
  3. C.Inversion of chromosome segment
  4. D.Duplication of chromosome arm
Q 27 :
The presence of an extra chromosome resulting in 2n+1 condition is termed?
  1. A.Euploidy
  2. B.Aneuploidy
  3. C.Polyploidy
  4. D.Haploidy
Q 28 :
Down syndrome is caused by trisomy of which chromosome?
  1. A.18
  2. B.13
  3. C.21
  4. D.X
Q 29 :
Karyotyping is most useful for detecting?
  1. A.Chromosomal number and structural abnormalities
  2. B.Point mutations
  3. C.Gene expression levels
  4. D.Protein folding errors
Q 30 :
A pericentric inversion includes the?
  1. A.Telomere only
  2. B.q arm only
  3. C.p arm only
  4. D.Centromere
Q 31 :
Which genetic cross reveals independent assortment?
  1. A.Monohybrid cross
  2. B.Dihybrid cross
  3. C.Test cross
  4. D.Back cross
Q 32 :
The Hardy–Weinberg principle assumes all except?
  1. A.Random mating
  2. B.No mutation
  3. C.Large population size
  4. D.Natural selection present
Q 33 :
In Hardy–Weinberg equilibrium, the frequency of heterozygotes is represented by?
  1. A.p²
  2. B.2pq
  3. C.q²
  4. D.p + q
Q 34 :
Epistasis refers to interaction between?
  1. A.Alleles of same gene
  2. B.Chromosomes
  3. C.Non-allelic genes
  4. D.Codons
Q 35 :
Which chromosomal deletion is typically lethal?
  1. A.Terminal deletion
  2. B.Interstitial deletion
  3. C.Microdeletion
  4. D.Large segment deletion
Q 36 :
Wild-type allele refers to the allele that is?
  1. A.Mutated
  2. B.Most common in population
  3. C.Recessive
  4. D.Lethal
Q 37 :
Back cross is performed between hybrid and?
  1. A.Another hybrid
  2. B.Any recessive individual
  3. C.Either parent
  4. D.Any homozygous individual
Q 38 :
Which ratio is expected in a monohybrid cross involving complete dominance in F2 generation?
  1. A.3:1
  2. B.1:1
  3. C.9:3:3:1
  4. D.1:2:1
Q 39 :
A cross between an individual of unknown genotype and a homozygous recessive individual is called?
  1. A.Back cross
  2. B.Reciprocal cross
  3. C.Test cross
  4. D.Dihybrid cross
Q 40 :
Which chromosomal abnormality results from unequal crossing over?
  1. A.Translocation
  2. B.Duplication
  3. C.Inversion
  4. D.Aneuploidy
Q 41 :
Euploidy refers to variation in chromosome number involving?
  1. A.Gain or loss of one chromosome
  2. B.Structural rearrangement
  3. C.Gain or loss of whole chromosome sets
  4. D.Partial chromosome deletion
Q 42 :
Turner syndrome is an example of?
  1. A.Monosomy X
  2. B.Polyploidy
  3. C.Trisomy
  4. D.Autosomal aneuploidy
Q 43 :
Barr body represents?
  1. A.Inactive X chromosome
  2. B.Active X chromosome
  3. C.Y chromosome
  4. D.Autosomal heterochromatin
Q 44 :
Which structure ensures correct segregation of chromosomes during mitosis?
  1. A.Telomere
  2. B.Nucleolus
  3. C.Kinetochore
  4. D.Chromatin loop
Q 45 :
The centromere is composed mainly of?
  1. A.Euchromatin
  2. B.Histone H1
  3. C.rRNA genes
  4. D.Satellite DNA
Q 46 :
Which type of epistasis modifies the classical 9:3:3:1 ratio to 12:3:1?
  1. A.Complementary epistasis
  2. B.Recessive epistasis
  3. C.Dominant epistasis
  4. D.Duplicate genes
Q 47 :
Hardy–Weinberg equilibrium will be disturbed by which factor?
  1. A.Random mating
  2. B.Large population size
  3. C.Absence of mutation
  4. D.Migration
Q 48 :
Alleles occupying the same position on homologous chromosomes are called?
  1. A.Linked genes
  2. B.Codominant genes
  3. C.Homologous genes
  4. D.Gene loci
Q 49 :
A hybrid individual contains?
  1. A.Identical alleles
  2. B.Only recessive alleles
  3. C.Lethal alleles
  4. D.Dissimilar alleles
Q 50 :
Structural variation involving reversal of a chromosome segment is termed?
  1. A.Translocation
  2. B.Duplication
  3. C.Inversion
  4. D.Deletion

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