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Latest Pharmacy Exams Exam Question (Objective Questions), MCQ in English

Subjects : Pharmacy

Question Bank Pharmacy Exams - English
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Pharmacy

Question 1Single Answer
Which preparation is used to help prevent dehydration or achieve rehydration?
  1. A
    Lytren solution
  2. B
    Liposul
  3. C
    Bicytra
  4. D
    Mylicon
Question 2Single Answer
Emulsions prepared using Tweens as the principal emulsifying agents are usually of which type?
  1. A
    Water-in-oil
  2. B
    Oil-in-water
  3. C
    Multiple emulsion
  4. D
    Microcapsule dispersion
  5. E
     reversible
Question 3Single Answer
Compared with the corresponding crystalline form, an amorphous form of a drug is generally?
  1. A
    Less soluble
  2. B
    More soluble
  3. C
    Chemically identical to a solvate
  4. D
    Completely insoluble
Question 4Single Answer
A triple-roller mill is particularly useful in pharmaceutical preparation for reducing particle size and producing smooth?
  1. A
    Ointments
  2. B
    Hard gelatin capsules
  3. C
    Aerosols
  4. D
    Suppository molds
Question 5Single Answer
Particle-size reduction is most likely to improve drug absorption when absorption is limited primarily by which process?
  1. A
    Dissolution of a poorly soluble drug
  2. B
    Renal filtration
  3. C
    Hepatic metabolism
  4. D
    Plasma-protein synthesis
Question 6Single Answer
A material whose apparent viscosity increases as shear rate increases is classified as?
  1. A
    Dilatant
  2. B
    Newtonian
  3. C
    Pseudoplastic
  4. D
    Thixotropic
Question 7Single Answer
A solution contains 3 grains of a drug per US fluid ounce. Approximately what is its percentage strength w/v?
  1. A
    0.66%
  2. B
    0.20%
  3. C
    1.50%
  4. D
    6.60%
Question 8Single Answer
Cyanocobalamin is which type of substance?
  1. A
    Steroid
  2. B
    Vitamin
  3. C
    Cholinesterase inhibitor
  4. D
    Enzyme
Question 9Single Answer
Tweens are best classified as which type of pharmaceutical excipient?
  1. A
    Nonionic surfactants
  2. B
    Phospholipids
  3. C
    Glycosides
  4. D
    Inorganic electrolytes
Question 10Single Answer
Which process can promote separation of an emulsion by accelerating movement of dispersed droplets?
  1. A
    Centrifugation
  2. B
    Buffering
  3. C
    Isotonization
  4. D
    Sweetening
Question 11Single Answer
Which gastrointestinal effect is characteristically associated with oral iron preparations?
  1. A
    Darkening of stools
  2. B
    Blue discoloration of saliva
  3. C
    Green discoloration of tears
  4. D
    Purple discoloration of sweat
Question 12Single Answer
Orally administered lidocaine has limited systemic usefulness largely because it undergoes extensive?
  1. A
    First-pass hepatic metabolism
  2. B
    Renal tubular secretion before absorption
  3. C
    Photochemical degradation in the stomach
  4. D
    Pulmonary metabolism before absorption
Question 13Single Answer
On exposure to air and light, phenol may gradually develop which discoloration because of oxidation?
  1. A
    Pink to reddish coloration
  2. B
    Bright green coloration
  3. C
    Deep blue coloration
  4. D
    Pure white coloration
Question 14Single Answer
Approximately how much HgCl₂ is required to prepare 1 US pint (about 473 mL) of a 1:5000 w/v solution?
  1. A
    9.5 mg
  2. B
    47.3 mg
  3. C
    94.6 mg
  4. D
    473 mg
Question 15Single Answer
Which sulfonylurea has historically been associated with potentiation of the antidiuretic action of vasopressin?
  1. A
    Chlorpropamide
  2. B
    Chloramphenicol
  3. C
    Phenytoin
  4. D
    Dicoumarol
Question 16Single Answer
Which two drug properties are commonly altered by pharmaceutical complexation?
  1. A
    Stability and solubility
  2. B
    Atomic number and density
  3. C
    Molecular formula and atomic mass
  4. D
    Radioactivity and isotopic abundance
Question 17Single Answer
If drug distribution into tissues occurs more slowly than elimination from plasma, what is most likely to occur initially?
  1. A
    Failure to rapidly attain distribution equilibrium
  2. B
    Immediate pharmacodynamic tolerance
  3. C
    Complete inhibition of metabolism
  4. D
    Irreversible plasma-protein binding
Question 18Single Answer
In pharmaceutical aerosol terminology, PSIG stands for?
  1. A
    Pounds per square inch gauge
  2. B
    Pressure standard in glass
  3. C
    Pounds per square inch gravity
  4. D
    Propellant strength in grams
Question 19Single Answer
In the older terminology of radiation protection, the abbreviation rem stands for?
  1. A
    Roentgen equivalent man
  2. B
    Radiation emission meter
  3. C
    Relative electron mass
  4. D
    Roentgen exposure measurement
Question 20Single Answer
Azathioprine is primarily classified as a?
  1. A
    Immunosuppressant
  2. B
    Cardiotonic
  3. C
    Antacid
  4. D
    Local anesthetic
Question 21Single Answer
Phenol has which property with respect to water at ordinary conditions?
  1. A
    It has appreciable but limited solubility in water
  2. B
    It is completely immiscible with water
  3. C
    It is a carboxylic acid
  4. D
    It is an inorganic base
Question 22Single Answer
The pH of an aqueous solution is fundamentally related to the activity of which ion?
  1. A
    Hydrogen ion
  2. B
    Sodium ion
  3. C
    Chloride ion
  4. D
    Calcium ion
Question 23Single Answer
Which tissue commonly serves as an important storage site for highly lipid-soluble drugs?
  1. A
    Adipose tissue
  2. B
    Corneal epithelium
  3. C
    Dental enamel
  4. D
    Nail plate
Question 24Single Answer
Extensive distribution or sequestration of a drug in tissues is commonly associated with which pharmacokinetic finding?
  1. A
    Large apparent volume of distribution
  2. B
    Zero clearance
  3. C
    Complete absence of metabolism
  4. D
    Very small apparent volume of distribution
Question 25Single Answer
Oxytocin may be administered clinically to?
  1. A
    Induce or augment labor
  2. B
    Prevent fertilization
  3. C
    Treat male hypogonadism
  4. D
    Produce chronic hypertension
Question 26Single Answer
Which antibiotic is acid-labile and therefore undergoes substantial degradation in the acidic environment of the stomach?
  1. A
    Penicillin G
  2. B
    Acetaminophen
  3. C
    Hydrocortisone
  4. D
    Aspirin
Question 27Single Answer
A surfactant can increase the dissolution of a poorly water-soluble drug primarily by improving?
  1. A
    Wetting and interfacial contact
  2. B
    Nuclear decay
  3. C
    Renal filtration pressure
  4. D
    Hepatic blood formation
Question 28Single Answer
Which drug is known to produce blue fluorescence of urine under ultraviolet light?
  1. A
    Triamterene
  2. B
    Riboflavin
  3. C
    Nitrofurantoin
  4. D
    Cascara
Question 29Single Answer
Extensive plasma-protein binding generally affects drug biotransformation by?
  1. A
    Slowing metabolism of the bound fraction
  2. B
    Completely preventing metabolite formation
  3. C
    Converting metabolism to renal filtration
  4. D
    Always accelerating hepatic metabolism
Question 30Single Answer
Celestone Soluspan contains formulations of which corticosteroid?
  1. A
    Betamethasone
  2. B
    Dexamethasone
  3. C
    Prednisone
  4. D
    Cortisone
Question 31Single Answer
The site and timing of drug release from an enteric-coated tablet depend strongly on gastrointestinal?
  1. A
    pH and transit conditions
  2. B
    Blood group
  3. C
    Respiratory rate alone
  4. D
    Skin temperature alone
Question 32Single Answer
Carbolic acid is another name for?
  1. A
    Phenol
  2. B
    Benzoic acid
  3. C
    Salicylic acid
  4. D
    Acetylsalicylic acid
Question 33Single Answer
Which dosage-form approach is commonly used to improve palatability by masking an unpleasant drug taste?
  1. A
    Taste-masking formulation
  2. B
    Increasing particle contamination
  3. C
    Removing all excipients
  4. D
    Increasing microbial load
Question 34Single Answer
Which medium used in compendial sterility testing is suitable for detecting fungi as well as aerobic bacteria?
  1. A
    Soybean–casein digest medium
  2. B
    Fluid thioglycollate medium only
  3. C
    Distilled water
  4. D
    Physiological saline alone
Question 35Single Answer
When a product contains an antimicrobial substance that could interfere with a sterility test, the test method should?
  1. A
    Neutralize or remove the antimicrobial activity appropriately
  2. B
    Automatically declare the product sterile
  3. C
    Omit incubation
  4. D
    Perform only a visual color test
Question 36Single Answer
Which medium is primarily intended for detection of anaerobic bacteria during compendial sterility testing?
  1. A
    Fluid thioglycollate medium
  2. B
    Purified water
  3. C
    Lactose solution
  4. D
    Mineral oil
Question 37Single Answer
Which factor can significantly alter the hepatic metabolism of another drug?
  1. A
    Enzyme induction or inhibition
  2. B
    Tablet color alone
  3. C
    Capsule shell color alone
  4. D
    Prescription handwriting style
Question 38Single Answer
What is the principal pharmaceutical role of potassium iodide in strong iodine solution?
  1. A
    Increasing the aqueous solubility of iodine
  2. B
    Acting as the main preservative
  3. C
    Increasing solution viscosity
  4. D
    Producing an emulsion
Question 39Single Answer
Which organic nitrate is commonly used for rapid relief of an acute anginal attack when administered sublingually?
  1. A
    Nitroglycerin
  2. B
    Warfarin
  3. C
    Digoxin
  4. D
    Hydrochlorothiazide
Question 40Single Answer
The usual adult dose of a drug is 6 grains. According to Young's rule, what dose is calculated for a 6-year-old child?
  1. A
    1 grain
  2. B
    2 grains
  3. C
    3 grains
  4. D
    4 grains
Question 41Single Answer
Which storage condition is appropriate for morphine sulfate tablets according to current product labeling?
  1. A
    Dispense in a tight, light-resistant container
  2. B
    Store permanently exposed to direct sunlight
  3. C
    Store in an open container
  4. D
    Immerse the tablets in water
Question 42Single Answer
Which plant is an important natural source of the anticancer vinca alkaloids vincristine and vinblastine?
  1. A
    Catharanthus roseus
  2. B
    Digitalis purpurea
  3. C
    Atropa belladonna
  4. D
    Strychnos nux-vomica
Question 43Single Answer
How much zinc sulfate is required to prepare 30 mL of a 1:500 w/v solution?
  1. A
    30 mg
  2. B
    60 mg
  3. C
    150 mg
  4. D
    500 mg
Question 44Single Answer
If a CNS-active drug is extensively ionized at blood pH, its passive penetration across the blood-brain barrier will generally be?
  1. A
    Slower
  2. B
    Faster
  3. C
    Independent of ionization
  4. D
    Instantaneous
Question 45Single Answer
Formation of a more soluble salt of an ionizable drug is commonly used primarily to improve its?
  1. A
    Aqueous solubility
  2. B
    Atomic number
  3. C
    Radioactivity
  4. D
    Isotopic composition
Question 46Single Answer
To reduce gastrointestinal irritation associated with niacin, patients are commonly advised to take immediate-release niacin?
  1. A
    With food
  2. B
    Only on an empty stomach
  3. C
    Only with antacids
  4. D
    Only after prolonged fasting
Question 47Single Answer
A drug with a biological half-life of 6.9 days would generally be expected to require which dosing pattern compared with a drug having a half-life of only a few hours, assuming other pharmacokinetic factors are similar?
  1. A
    Less frequent dosing
  2. B
    More frequent dosing
  3. C
    Continuous dosing every minute
  4. D
    A dosing interval unrelated to pharmacokinetics
Question 48Single Answer
Tween 20 is best classified as a?
  1. A
    Hydrophilic nonionic surfactant
  2. B
    Lipophilic ionic surfactant
  3. C
    Strong inorganic acid
  4. D
    Chelating metal ion
Question 49Single Answer
Which pharmacokinetic property does not directly determine the rate at which a drug is absorbed from a solution at its absorption site?
  1. A
    Elimination half-life
  2. B
    Solution viscosity
  3. C
    Drug complexation
  4. D
    Micellar solubilization
Question 50Single Answer
For a drug eliminated by first-order kinetics, the elimination half-life is given by which expression?
  1. A
    0.693/k
  2. B
    k/0.693
  3. C
    1/k²
  4. D
    2k
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