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Latest Pharmacy Officer Exam Question (Objective Questions), MCQ in English

Subjects : Pharmacy Officer

Question Bank Pharmacy Officer Exam - English
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Pharmacy Officer

Question 1Single Answer
The characteristic odour of onion bulbs is attributed to:
  1. A
    Quercetin glycosides   
  2. B
    furostanol glycosides
  3. C
    Heterogeneous suphated polysaccharides  
  4. D
    Alkyl or alkenyl disulphides
Question 2Single Answer
The chief constituent of the seeds strophanthus gratus or woods of Acokanthere schimiperi belonging to the family Apocynaceae is G-stropanthin. On hydrolysis, it gives:
  1. A
    Scilarenin      
  2. B
    Ouabagenin
  3. C
    Cannogenin      
  4. D
    Diosgenin
Question 3Single Answer
The duration of action of sublingual nitroglycerin tablet is:
  1. A
    8-10 hours  
  2. B
    4-8 hours
  3. C
    1-3 minutes  
  4. D
    2-5 minutes
Question 4Single Answer
Identify the adrenergic receptor, whose agonists can be missed used by sportsmen for Anabolic effects:
  1. A
    a1            
  2. B
    a2
  3. C
    β1       
  4. D
    β 2
Question 5Single Answer
When the urinary pH becomes 8.0, significant increase in the excretion of the drugs Takes places:
  1. A
    Mepyramine
  2. B
    Aspirin
  3. C
    Morphine     
  4. D
    Mecamylamine
Question 6Single Answer
Condensation of 6-Hydroxy-2,4,5-triaminopyridine with 1.13-trichloro acetone and N-(4-aminobenzoyl) glutamic acid at pH 4 to 5, in the presence of sodium bisulphate gives:
  1. A
    Pteroyl glutarmic acid   
  2. B
    Amethoterin
  3. C
    Triamtereme 
  4. D
    Acyclovir
Question 7Single Answer
The common structural feature of iodoxamic acid, iotalmic acid, diatrizoic acid and iocarmic acid is:
  1. A
    Sulphonaphthalein   
  2. B
    2,4,6-tri-iodo benzoic acid
  3. C
    Tri-ido triphenyl methanoic acid  
  4. D
    Tri-ido diphenyl methanoic acid
Question 8Single Answer
List of diseases and ailments which a drug may not purport to prevent or cure or make claims to prevent or cure under the Drugs and Cosmetics Rule 1945 is given under:
  1. A
    Schedule J         
  2. B
    Schedule K
  3. C
    Schedule M      
  4. D
    Schedule P
Question 9Single Answer
Annato consists of the dried seeds of Bixa orellana L-Family Bxaceae. The chief Constituent is:
  1. A
    Triterpene alcohol   
  2. B
    Crocin and crocetin
  3. C
    Capsanthin   
  4. D
    Carotenoids
Question 10Single Answer
To identify the emulsion type, which of the following tests are conducted ?
  1. A
    Dilution test
  2. B
    Dye test
  3. C
    Conductivity test
  4. D
    All
Question 11Single Answer
‘Cresol with soap solution’ is a preparation, in which soap in incorporated to:
  1. A
    Impact detergent property
  2. B
    Improve mutual miscibility of cresol and water by Reducing critical solution temperature of cresol-water system
  3. C
    Sustain the germicidal action of cresol
  4. D
    Improve the stability of cresol
Question 12Single Answer
When stoichiometric amount of CaCl2 is added to an emulsion stabilized with sodium alginate, it will:
  1. A
    Crack immediately
  2. B
    Change the nature from w/o to o/w
  3. C
    Change the nature from o/w to w/o
  4. D
    Accelerate the phenomenon of Oswald ripening
Question 13Single Answer
Chlorine and bromine substitution in aromatic compounds:
  1. A
    Enhances fluorescence 
  2. B
    Does not change the fluorescence
  3. C
    Quenches the fluorescence  
  4. D
    Removes the fluorescence
Question 14Single Answer
Solvent programming, also called gradient elution, involves:
  1. A
    Changing the column length  
  2. B
    Changing the mobile phase composition
  3. C
    Using the mobile phase in unchanged    
  4. D
    Successive injection of sample
Question 15Single Answer
Calibration of the cell constant of conductance cell is carried out by using a solution:
  1. A
    0.1 M NaCl     
  2. B
    0.1 M CaCl2
  3. C
    0.1 M KCl            
  4. D
    0.1 M AlCl3
Question 16Single Answer
Hybridoma technology is widely used for producing:
  1. A
    Callus culture
  2. B
    Organ culture
  3. C
    Monoclonal antibodies    
  4. D
    Attenuated microorganism
Question 17Single Answer
 ‘Gene therapy’ refers to the process of:
  1. A
    Identifying disease causing genes and activating them for therapeutic benefits        
  2. B
    Increasing the expression levels of the set of genes involved in a given disease in affected cells through selective modulating agents
  3. C
    Transfer of new genetic material to the cells of an individual for therapeutic benefit
  4. D
    Removal of the protein corresponding to the disease casing genes from the cells of the affected individual
Question 18Single Answer
A technician is attempting to sterilize a plug of cotton in hermetically sealed condition in a glass bottle by autoclaving. Which of the following statement is correct?
  1. A
    It should be sterilized at 115-1180C for 30 minutes
  2. B
    It should be sterilized at 121 to 1240C for 15 minutes at 15 lbs/sq. inch pressure
  3. C
    Sterilization cannot be achieved
  4. D
    It should be autoclaved at 126-1290C with saturated steam for 10 minutes
Question 19Single Answer
Hyperuricamia is associated with the abnormal metabolism of:
  1. A
    Pyrimidine      ine
  2. B
    Purine
  3. C
    Riboflavin    
  4. D
    Thiam
Question 20Single Answer
What is the concentration of NaCl required making 1% solution of cocaine HCl Isotonic with blood plasma? Freezing point of 1% w/v solution of NaCl is -0.5760 C and freezing point of 1% w/v cocaine HCl is -0.090 C [0.52 - a ¸ b]:
  1. A
    0.746% w/v    
  2. B
    0.9% w/v
  3. C
    0.5% w/v          
  4. D
    0.373% w/v
Question 21Single Answer
Arillode is:
  1. A
    Warty out –growth from micropyle ,e.g. castor 
  2. B
    Succulent growth from hillium covering the entire seeds e.g. nutmeg
  3. C
    Outgrowth originating from micropyle and covering the seeds e.g cardamom
  4. D
    enlarged funicle e.g. colchicum seed
Question 22Single Answer
Cinnamon consists of the dried inner bark of the shoots of coppiced trees of Cinnamomumzeylanicum Nees. The typical microscopic characters of the bark are:
  1. A
    Biseriate Medullary Rays, secretory cavities containing volatile oil mucilage and few starch grains in cortical parenchyma and calcium oxalate in parenchymatous cells.
  2. B
    2-5 layers of cork cells containing oil globules. Presence of schizogenous canal
  3. C
    Medullary rays multiseriate, the periderm portion cork has both tangentially and radially elongated cells, stones cells present and no phloem fibres
  4. D
    Ex-foliated cork, non-lignified with 2-4 layers of phellogen. 15-20 rows of phelloderm. Prominent vascular tissue.
Question 23Single Answer
An essential ingredient in the general preparation of plant tissue cultural media is
  1. A
    Auxin or naphthalene acetic acid    
  2. B
    Sucrose or Glucose
  3. C
    Gibberlin G1 or Gibberlin G2   
  4. D
    Pyridoxine HCl
Question 24Single Answer
The drugs mefloquine, proguanil and primaquine can be effectively used in diseases produced by:
  1. A
    Mycoplasma     
  2. B
    Dermatophytes
  3. C
    Protozoa         
  4. D
    Spirochaetes
Question 25Single Answer
Identify the receptor which demonstrates the fastest onset of response, when stimulated.
  1. A
    Nuclear receptors     
  2. B
    Ionotropic receptors
  3. C
    G-protein coupled receptors  
  4. D
    Insulin receptor
Question 26Single Answer
Which preparation is used to help prevent dehydration or achieve rehydration?
  1. A
    Lytren solution
  2. B
    Liposul
  3. C
    Bicytra
  4. D
    Mylicon
Question 27Single Answer
Emulsions prepared using Tweens as the principal emulsifying agents are usually of which type?
  1. A
    Water-in-oil
  2. B
    Oil-in-water
  3. C
    Multiple emulsion
  4. D
    Microcapsule dispersion
  5. E
     reversible
Question 28Single Answer
Compared with the corresponding crystalline form, an amorphous form of a drug is generally?
  1. A
    Less soluble
  2. B
    More soluble
  3. C
    Chemically identical to a solvate
  4. D
    Completely insoluble
Question 29Single Answer
A triple-roller mill is particularly useful in pharmaceutical preparation for reducing particle size and producing smooth?
  1. A
    Ointments
  2. B
    Hard gelatin capsules
  3. C
    Aerosols
  4. D
    Suppository molds
Question 30Single Answer
Particle-size reduction is most likely to improve drug absorption when absorption is limited primarily by which process?
  1. A
    Dissolution of a poorly soluble drug
  2. B
    Renal filtration
  3. C
    Hepatic metabolism
  4. D
    Plasma-protein synthesis
Question 31Single Answer
A material whose apparent viscosity increases as shear rate increases is classified as?
  1. A
    Dilatant
  2. B
    Newtonian
  3. C
    Pseudoplastic
  4. D
    Thixotropic
Question 32Single Answer
A solution contains 3 grains of a drug per US fluid ounce. Approximately what is its percentage strength w/v?
  1. A
    0.66%
  2. B
    0.20%
  3. C
    1.50%
  4. D
    6.60%
Question 33Single Answer
Cyanocobalamin is which type of substance?
  1. A
    Steroid
  2. B
    Vitamin
  3. C
    Cholinesterase inhibitor
  4. D
    Enzyme
Question 34Single Answer
Tweens are best classified as which type of pharmaceutical excipient?
  1. A
    Nonionic surfactants
  2. B
    Phospholipids
  3. C
    Glycosides
  4. D
    Inorganic electrolytes
Question 35Single Answer
Which process can promote separation of an emulsion by accelerating movement of dispersed droplets?
  1. A
    Centrifugation
  2. B
    Buffering
  3. C
    Isotonization
  4. D
    Sweetening
Question 36Single Answer
Which gastrointestinal effect is characteristically associated with oral iron preparations?
  1. A
    Darkening of stools
  2. B
    Blue discoloration of saliva
  3. C
    Green discoloration of tears
  4. D
    Purple discoloration of sweat
Question 37Single Answer
Orally administered lidocaine has limited systemic usefulness largely because it undergoes extensive?
  1. A
    First-pass hepatic metabolism
  2. B
    Renal tubular secretion before absorption
  3. C
    Photochemical degradation in the stomach
  4. D
    Pulmonary metabolism before absorption
Question 38Single Answer
On exposure to air and light, phenol may gradually develop which discoloration because of oxidation?
  1. A
    Pink to reddish coloration
  2. B
    Bright green coloration
  3. C
    Deep blue coloration
  4. D
    Pure white coloration
Question 39Single Answer
Approximately how much HgCl₂ is required to prepare 1 US pint (about 473 mL) of a 1:5000 w/v solution?
  1. A
    9.5 mg
  2. B
    47.3 mg
  3. C
    94.6 mg
  4. D
    473 mg
Question 40Single Answer
Which sulfonylurea has historically been associated with potentiation of the antidiuretic action of vasopressin?
  1. A
    Chlorpropamide
  2. B
    Chloramphenicol
  3. C
    Phenytoin
  4. D
    Dicoumarol
Question 41Single Answer
Which two drug properties are commonly altered by pharmaceutical complexation?
  1. A
    Stability and solubility
  2. B
    Atomic number and density
  3. C
    Molecular formula and atomic mass
  4. D
    Radioactivity and isotopic abundance
Question 42Single Answer
If drug distribution into tissues occurs more slowly than elimination from plasma, what is most likely to occur initially?
  1. A
    Failure to rapidly attain distribution equilibrium
  2. B
    Immediate pharmacodynamic tolerance
  3. C
    Complete inhibition of metabolism
  4. D
    Irreversible plasma-protein binding
Question 43Single Answer
In pharmaceutical aerosol terminology, PSIG stands for?
  1. A
    Pounds per square inch gauge
  2. B
    Pressure standard in glass
  3. C
    Pounds per square inch gravity
  4. D
    Propellant strength in grams
Question 44Single Answer
In the older terminology of radiation protection, the abbreviation rem stands for?
  1. A
    Roentgen equivalent man
  2. B
    Radiation emission meter
  3. C
    Relative electron mass
  4. D
    Roentgen exposure measurement
Question 45Single Answer
Azathioprine is primarily classified as a?
  1. A
    Immunosuppressant
  2. B
    Cardiotonic
  3. C
    Antacid
  4. D
    Local anesthetic
Question 46Single Answer
Phenol has which property with respect to water at ordinary conditions?
  1. A
    It has appreciable but limited solubility in water
  2. B
    It is completely immiscible with water
  3. C
    It is a carboxylic acid
  4. D
    It is an inorganic base
Question 47Single Answer
The pH of an aqueous solution is fundamentally related to the activity of which ion?
  1. A
    Hydrogen ion
  2. B
    Sodium ion
  3. C
    Chloride ion
  4. D
    Calcium ion
Question 48Single Answer
Which tissue commonly serves as an important storage site for highly lipid-soluble drugs?
  1. A
    Adipose tissue
  2. B
    Corneal epithelium
  3. C
    Dental enamel
  4. D
    Nail plate
Question 49Single Answer
Extensive distribution or sequestration of a drug in tissues is commonly associated with which pharmacokinetic finding?
  1. A
    Large apparent volume of distribution
  2. B
    Zero clearance
  3. C
    Complete absence of metabolism
  4. D
    Very small apparent volume of distribution
Question 50Single Answer
Oxytocin may be administered clinically to?
  1. A
    Induce or augment labor
  2. B
    Prevent fertilization
  3. C
    Treat male hypogonadism
  4. D
    Produce chronic hypertension
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