Download AppGovt. JobsFree G.K. & Current AffairsScholarshipBlog
Free PracticeContact
📚 Exam by Category
▾
Objective Questions

Latest UP PGT Life Science Exam Question (Objective Questions), MCQ in English

Subjects : Concerned Subject (Life Science), General Studies

Question Bank UP PGT Life Science Exam - English
Back to Exam

Concerned Subject (Life Science)

Question 1Single Answer
Which interaction contributes most strongly to the stabilization of the hydrophobic core of a globular protein?
  1. A
    Hydrophobic interaction
  2. B
    Ionic bond formation
  3. C
    Covalent cross-linking
  4. D
    Coordination bonding
Question 2Single Answer
The peptide bond has partial double-bond character primarily because of?
  1. A
    Rotation around the Cα–C bond
  2. B
    Hydrogen bonding between adjacent residues
  3. C
    Resonance between carbonyl oxygen and amide nitrogen
  4. D
    Interaction between side chains
Question 3Single Answer
Which amino acid most strongly disrupts an α-helix when present within its interior?
  1. A
    Alanine
  2. B
    Leucine
  3. C
    Methionine
  4. D
    Proline
Question 4Single Answer
The Ramachandran plot represents permissible conformations involving rotation around?
  1. A
    C–N peptide bonds only
  2. B
    N–Cα and Cα–C bonds
  3. C
    Cα–R group bonds
  4. D
    Carbonyl C–O bonds
Question 5Single Answer
Which amino acid lacks a chiral α-carbon?
  1. A
    Serine
  2. B
    Glycine
  3. C
    Valine
  4. D
    Threonine
Question 6Single Answer
In β-sheets, hydrogen bonds are mainly formed between?
  1. A
    Backbone carbonyl and amide groups
  2. B
    Side-chain amino groups
  3. C
    Adjacent hydrophobic side chains
  4. D
    Terminal carboxyl groups
Question 7Single Answer
Which level of protein structure describes the spatial arrangement of different polypeptide chains?
  1. A
    Primary structure
  2. B
    Quaternary structure
  3. C
    Tertiary structure
  4. D
    Secondary structure
Question 8Single Answer
Which amino acid is most likely to participate in disulfide bond formation?
  1. A
    Tryptophan
  2. B
    Histidine
  3. C
    Tyrosine
  4. D
    Cysteine
Question 9Single Answer
A protein at its isoelectric point generally has?
  1. A
    Zero net electrical charge
  2. B
    Maximum net negative charge
  3. C
    Maximum net positive charge
  4. D
    Complete loss of secondary structure
Question 10Single Answer
Which force is most important in determining the specificity of enzyme-substrate binding?
  1. A
    Phosphodiester linkages
  2. B
    Permanent covalent bonds
  3. C
    Metallic interactions
  4. D
    Multiple weak noncovalent interactions
Question 11Single Answer
Competitive inhibition of an enzyme typically causes?
  1. A
    Increase in apparent Km with unchanged Vmax
  2. B
    Decrease in Km and Vmax
  3. C
    Decrease in Vmax with unchanged Km
  4. D
    Increase in both Km and Vmax
Question 12Single Answer
A pure noncompetitive inhibitor generally causes?
  1. A
    Increased Km only
  2. B
    Reduced Vmax without altering Km
  3. C
    Increased Vmax
  4. D
    Reduced Km and increased Vmax
Question 13Single Answer
The Michaelis constant Km corresponds to substrate concentration at which reaction velocity is?
  1. A
    One-fourth of Vmax
  2. B
    Equal to Vmax
  3. C
    Twice Vmax
  4. D
    Half of Vmax
Question 14Single Answer
Which enzyme class catalyzes transfer of functional groups from one molecule to another?
  1. A
    Hydrolases
  2. B
    Isomerases
  3. C
    Ligases
  4. D
    Transferases
Question 15Single Answer
Enzymes accelerate reactions primarily by?
  1. A
    Increasing reaction free-energy change
  2. B
    Increasing substrate free energy
  3. C
    Shifting equilibrium permanently
  4. D
    Lowering activation energy
Question 16Single Answer
Allosteric enzymes commonly exhibit which type of substrate-velocity curve?
  1. A
    Hyperbolic
  2. B
    Linear
  3. C
    Sigmoidal
  4. D
    Biphasic exponential
Question 17Single Answer
The catalytic efficiency of an enzyme under low substrate concentration is best represented by?
  1. A
    kcat/Km
  2. B
    Km/Vmax
  3. C
    Vmax × Km
  4. D
    Vmax/kcat
Question 18Single Answer
Which coenzyme is derived from niacin?
  1. A
    FAD
  2. B
    Coenzyme A
  3. C
    NAD+
  4. D
    Tetrahydrofolate
Question 19Single Answer
FAD is derived from which vitamin?
  1. A
    Thiamine
  2. B
    Pyridoxine
  3. C
    Biotin
  4. D
    Riboflavin
Question 20Single Answer
Which vitamin functions as a precursor of thiamine pyrophosphate?
  1. A
    Vitamin B12
  2. B
    Vitamin B2
  3. C
    Vitamin B6
  4. D
    Vitamin B1
Question 21Single Answer
Glycogen differs structurally from amylopectin mainly because glycogen has?
  1. A
    β-1,4 glycosidic bonds
  2. B
    Only linear glucose chains
  3. C
    No reducing ends
  4. D
    More frequent α-1,6 branch points
Question 22Single Answer
Cellulose consists of glucose units joined by?
  1. A
    α-1,4 linkages
  2. B
    β-1,4 linkages
  3. C
    α-1,6 linkages
  4. D
    β-1,6 linkages
Question 23Single Answer
Which carbohydrate is a nonreducing disaccharide?
  1. A
    Maltose
  2. B
    Sucrose
  3. C
    Lactose
  4. D
    Cellobiose
Question 24Single Answer
The major structural difference between RNA and DNA sugars occurs at which carbon?
  1. A
    1′ carbon
  2. B
    5′ carbon
  3. C
    3′ carbon
  4. D
    2′ carbon
Question 25Single Answer
Which nitrogenous base occurs normally in RNA but not DNA?
  1. A
    Uracil
  2. B
    Cytosine
  3. C
    Adenine
  4. D
    Guanine
Question 26Single Answer
A phosphodiester bond in nucleic acids links?
  1. A
    Two nitrogenous bases
  2. B
    Two phosphate groups
  3. C
    3′ hydroxyl of one sugar with 5′ phosphate of another
  4. D
    Two ribose 2′ hydroxyl groups
Question 27Single Answer
Which form of DNA is the predominant conformation under physiological conditions?
  1. A
    A-DNA
  2. B
    B-DNA
  3. C
    Z-DNA
  4. D
    H-DNA
Question 28Single Answer
Z-DNA is characterized by?
  1. A
    Left-handed helical structure
  2. B
    Right-handed helical structure
  3. C
    Triple-stranded structure
  4. D
    Absence of base pairing
Question 29Single Answer
Which lipid is a major component of biological membranes?
  1. A
    Phospholipid
  2. B
    Triacylglycerol
  3. C
    Wax ester
  4. D
    Cholesteryl ester only
Question 30Single Answer
Cholesterol modulates membrane fluidity because it?
  1. A
    Completely prevents lipid movement
  2. B
    Buffers changes in membrane fluidity
  3. C
    Removes membrane proteins
  4. D
    Converts phospholipids into triglycerides
Question 31Single Answer
The fluid mosaic model of membrane structure was proposed by?
  1. A
    Watson and Crick
  2. B
    Jacob and Monod
  3. C
    Singer and Nicolson
  4. D
    Hodgkin and Huxley
Question 32Single Answer
Integral membrane proteins are usually removed from membranes using?
  1. A
    High salt concentration only
  2. B
    Chelating agents only
  3. C
    Mild changes in pH only
  4. D
    Detergents
Question 33Single Answer
Which membrane transport process directly consumes ATP?
  1. A
    Primary active transport
  2. B
    Facilitated diffusion
  3. C
    Simple diffusion
  4. D
    Osmosis
Question 34Single Answer
The Na+/K+-ATPase transports per cycle?
  1. A
    3 Na+ out and 2 K+ in
  2. B
    2 Na+ out and 3 K+ in
  3. C
    3 Na+ in and 2 K+ out
  4. D
    Equal amounts of Na+ and K+
Question 35Single Answer
A symporter transports?
  1. A
    Two substances in opposite directions
  2. B
    Ions through gap junctions
  3. C
    Only water molecules
  4. D
    Two substances in the same direction
Question 36Single Answer
Which organelle contains acid hydrolases involved in intracellular digestion?
  1. A
    Peroxisome
  2. B
    Centrosome
  3. C
    Nucleolus
  4. D
    Lysosome
Question 37Single Answer
Peroxisomes are especially important for?
  1. A
    Ribosomal assembly
  2. B
    Chromosome segregation
  3. C
    Glycosylation of proteins
  4. D
    Oxidation of very-long-chain fatty acids
Question 38Single Answer
Which organelle is the principal site of oxidative phosphorylation?
  1. A
    Golgi apparatus
  2. B
    Lysosome
  3. C
    Mitochondrion
  4. D
    Smooth endoplasmic reticulum
Question 39Single Answer
The mitochondrial electron transport chain is located mainly in the?
  1. A
    Outer mitochondrial membrane
  2. B
    Intermembrane space only
  3. C
    Matrix
  4. D
    Inner mitochondrial membrane
Question 40Single Answer
Which component of mitochondrial ATP synthase contains the catalytic sites for ATP formation?
  1. A
    F0 sector
  2. B
    F1 sector
  3. C
    Cytochrome c
  4. D
    Complex I
Question 41Single Answer
Rough endoplasmic reticulum is primarily associated with synthesis of?
  1. A
    Cytosolic proteins
  2. B
    Secretory and membrane proteins
  3. C
    Nuclear DNA
  4. D
    Glycogen
Question 42Single Answer
Signal recognition particle directs newly synthesized proteins to the?
  1. A
    Lysosome directly
  2. B
    Peroxisomal matrix
  3. C
    Nucleus
  4. D
    Rough endoplasmic reticulum
Question 43Single Answer
N-linked glycosylation of proteins begins in the?
  1. A
    Cytosol
  2. B
    Mitochondrial matrix
  3. C
    Nucleus
  4. D
    Endoplasmic reticulum
Question 44Single Answer
The cis face of the Golgi apparatus mainly receives vesicles from the?
  1. A
    Plasma membrane
  2. B
    Endoplasmic reticulum
  3. C
    Lysosome
  4. D
    Nucleus
Question 45Single Answer
Mannose-6-phosphate functions as a sorting signal for proteins destined to?
  1. A
    Lysosomes
  2. B
    Mitochondria
  3. C
    Peroxisomes
  4. D
    Nuclei
Question 46Single Answer
Microtubules are polymers of?
  1. A
    Actin
  2. B
    Myosin
  3. C
    Tubulin
  4. D
    Keratin
Question 47Single Answer
Which motor protein generally moves cargo toward the plus end of microtubules?
  1. A
    Dynein
  2. B
    Kinesin
  3. C
    Myosin II
  4. D
    Spectrin
Question 48Single Answer
Cytoplasmic dynein generally transports cargo toward the?
  1. A
    Minus end of microtubules
  2. B
    Plus end of microtubules
  3. C
    Barbed end of actin only
  4. D
    Extracellular matrix
Question 49Single Answer
Microfilaments are primarily composed of?
  1. A
    Tubulin
  2. B
    Laminin
  3. C
    Actin
  4. D
    Collagen
Question 50Single Answer
Intermediate filaments primarily provide cells with?
  1. A
    ATP synthesis
  2. B
    Mechanical strength
  3. C
    DNA replication
  4. D
    Vesicular transport
Important Questions Package

UP PGT Life Science Exam Online Question Bank Package

Buy UP PGT Life Science Important Questions, MCQ, question answer in Hindi & English. It will help you to score high marks in UP PGT Life Science question bank 2026 in Online, PDF & Print study material.

+ Free Monthly Current Affairs, GK & more PDF Download
Sr.Package NameAmount
1.UP PGT Life Science Exam - Hindi
Description : 1000 Question with Answer
₹101 [₹500]
2.UP PGT Life Science Exam - Hindi
Description : 2000 Question with Answer
₹141 [₹500]
3.UP PGT Life Science Exam - Hindi
Description : 3000 Question with Answer
₹171 [₹500]
4.UP PGT Life Science Exam - Hindi
Description : 4000 Question with Answer
₹201 [₹500]
5.UP PGT Life Science Exam - Hindi
Description : 5000 Question with Answer
₹221 [₹500]
6.UP PGT Life Science Exam - English
Description : 1000 Question with Answer
₹101 [₹500]
7.UP PGT Life Science Exam - English
Description : 2000 Question with Answer
₹141 [₹500]
8.UP PGT Life Science Exam - English
Description : 3000 Question with Answer
₹171 [₹500]
9.UP PGT Life Science Exam - English
Description : 4000 Question with Answer
₹201 [₹500]
10.UP PGT Life Science Exam - English
Description : 5000 Question with Answer
₹221 [₹500]
Back to Exam
Question for UP PGT Life Science 2026 - Quiz / Questions / MCQ - Toppersexam